Hspa1a

Gene Symbol	Hspa1a
Entrez Gene	193740
Alt Symbol	Hsp70-3, Hsp70.3, Hsp72, hsp68, hsp70A1
Species	Mouse
Gene Type	protein-coding
Description	heat shock protein 1A
Other Description	68 kDa heat shock protein|heat shock 70 kDa protein 1A|heat shock 70 kDa protein 3|heat shock 70kDa protein 1A|heat shock protein, 70 kDa 3|inducible heat shock protein 70
Swissprots	Q9QWJ5 Q61697 Q61696 Q7TQD8
Accessions	AAA57233 AAC84169 ABK96811 BAA32523 BAA32525 EDL26710 Q61696 AK132331 AK160912 BAE36086 AK171820 BAE42680 BC032044 BC054782 AAH54782 BC157921 AAI57922 M12571 AAA57234 M12572 AAA57235 NM_010479 NP_034609
Function	In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Essential for STUB1-mediated ubiquitination and degradation of FOXP3 in regulatory T-cells (Treg) during inflammation. {ECO:0000250|UniProtKB:P08107}.
Subcellular Location	Cytoplasm {ECO:0000250}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. {ECO:0000250}.
Top Pathways	Toxoplasmosis, Estrogen signaling pathway, Epstein-Barr virus infection, Legionellosis, Influenza A

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Hsp70-3 CRISPR/Cas9 KO Plasmid (m) - sc-431448 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Mouse

Hsp70-3 HDR Plasmid (m) - sc-431448-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Mouse

Hsp70-3 Double Nickase Plasmid (m) - sc-431448-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Mouse

Hsp70-3 Double Nickase Plasmid (m2) - sc-431448-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Mouse

Hsp70-3 CRISPR Activation Plasmid (m) - sc-431448-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Mouse

Hsp70-3 CRISPR Activation Plasmid (m2) - sc-431448-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Mouse

Hsp70-3 Lentiviral Activation Particles (m) - sc-431448-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Mouse

Hsp70-3 Lentiviral Activation Particles (m2) - sc-431448-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Mouse

CompoZr® Knockout ZFN Kit - CKOZFN33519 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33519 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

HSPA1A siRNA (Mouse) - CRN1485 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Mouse

HSPA1A - MBS8240281 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Mouse

shRNA set against Mouse Hspa1a (NM_010479.2) - SHH315553 from Creative biogene Category siRNA Species Reactivities Mouse

HSPA1A shRNA Plasmid (Mouse) - CHN1485 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Mouse

HSPA1A miRNA 3'UTR clone - MiUTR1M-05828 from Creative biogene Species Reactivities Mouse

Search more