TNFSF10

Gene Symbol	TNFSF10
Entrez Gene	8743
Alt Symbol	APO2L, Apo-2L, CD253, TL2, TRAIL
Species	Human
Gene Type	protein-coding
Description	tumor necrosis factor (ligand) superfamily, member 10
Other Description	Apo-2 ligand|TNF-related apoptosis inducing ligand TRAIL|chemokine tumor necrosis factor ligand superfamily member 10|tumor necrosis factor (ligand) family, member 10|tumor necrosis factor apoptosis-inducing ligand splice variant delta|tumor necrosis factor ligand superfamily member 10
Swissprots	A1Y9B3 P50591
Accessions	ABK41891 CAH68809 CAL33971 CAZ39545 CCA94584 EAW78465 EAW78466 EAW78467 P50591 AK296085 BAG58840 AK309200 AK312742 BAG35612 AY312579 AAR16184 BC009795 BC020220 BC032722 AAH32722 BT019564 AAV38371 CR456895 CAG33176 DA041872 DA969653 DQ848564 ABI24016 DQ890873 ABM81799 DQ894029 ABM84955 EU183231 ABW24658 U37518 AAC50332 U57059 AAB01233 NM_001190942 NP_001177871 NM_001190943 NP_001177872 NM_003810 NP_003801 NR_033994
Function	Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
Subcellular Location	Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Tissue Specificity	Widespread; most predominant in spleen, lung and prostate.
Top Pathways	Cytokine-cytokine receptor interaction, Apoptosis, Natural killer cell mediated cytotoxicity, Measles, Influenza A

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-TNFSF10-cDNA-Clone - DC06489 from Abgent, a WuXi AppTec company Prices $379.35 Sizes 10 µg Species Human Accession BC032722

Mouse TRAIL/TNFSF10 (NP_033451) VersaClone cDNA - RDC0666 from R&D Systems Prices $199.00 Sizes 10 µg Species Mouse

TNFSF10 - MBS1274009 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC032722

Human TNFSF10 ORF Clone(NM_003810.3) - CDCL179240 from Creative Biomart Species Human Accession NM_003810.3

Human TNFSF10 ORF Clone(NM_001190942.1) - CDCL179241 from Creative Biomart Species Human Accession NM_001190942.1

Human TNFSF10 ORF Clone(NM_001190942.1) - CDCR358099 from Creative Biomart Species Human Accession NM_001190942.1

Human TNFSF10 ORF Clone(NM_001190942.1) - CDCR358100 from Creative Biomart Species Human Accession NM_001190942.1

Human TNFSF10 ORF Clone(NM_001190943.1) - CDCR358102 from Creative Biomart Species Human Accession NM_001190943.1

Human TNFSF10 ORF Clone(NM_001190943.1) - CDCR358106 from Creative Biomart Species Human Accession NM_001190943.1

Human TRAIL/TNFSF10 Gene ORF cDNA clone in cloning vector - HG10409-M from Sino Biological Species Human

Human TRAIL/TNFSF10 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10409-ACR from Sino Biological Species Human

Human TRAIL/TNFSF10 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10409-ACG from Sino Biological Species Human

Human TRAIL/TNFSF10 Gene ORF cDNA clone expression plasmid, N-His tag - HG10409-NH from Sino Biological Species Human

Human TRAIL/TNFSF10 Gene ORF cDNA clone expression plasmid, C-His tag - HG10409-CH from Sino Biological Species Human

Human TRAIL/TNFSF10 Gene ORF cDNA clone expression plasmid - HG10409-UT from Sino Biological Species Human

Human TRAIL/TNFSF10 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10409-NF from Sino Biological Species Human

Human TRAIL/TNFSF10 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10409-NM from Sino Biological Species Human

Human TRAIL/TNFSF10 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10409-CY from Sino Biological Species Human

Human TRAIL/TNFSF10 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10409-CF from Sino Biological Species Human

Human TRAIL/TNFSF10 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10409-NY from Sino Biological Species Human

Human TRAIL/TNFSF10 Gene ORF cDNA clone expression plasmid, C-His tag - HG10409-M-H from Sino Biological Species Human

Human TRAIL/TNFSF10 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10409-CM from Sino Biological Species Human

Human TNFSF10 ORF clone (NM_001190942.1) - CDCL150428 from Creative biogene Species Human

Human TNFSF10 ORF clone (NM_001190943.1) - CDCL150430 from Creative biogene Species Human

Human TNFSF10 ORF Clone (BC032722) - CDCS409223 from Creative biogene Species Human Accession P50591

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