Gene Symbol | Ecm1 |
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Entrez Gene | 13601 |
Alt Symbol | AI663821, p85 |
Species | Mouse |
Gene Type | protein-coding |
Description | extracellular matrix protein 1 |
Other Description | secretory component p85 |
Swissprots | Q3U5Q5 Q61508 |
Accessions | AAD13396 AAD13397 EDL38831 EDL38832 Q61508 AK153009 BAE31648 AK153471 BAE32022 AK159334 BAE34999 AK169939 BAE41471 BC138693 AAI38694 BC145381 AAI45382 BY224903 L33416 AAA37535 XM_006500984 XP_006501047 XM_006500985 XP_006501048 XM_011240008 XP_011238310 XM_011240009 XP_011238311 NM_001252653 NP_001239582 NM_007899 NP_031925 |
Function | Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix. |
Tissue Specificity | Expressed in the connective tissues surronding developing long bones, but not in the cartilage. The long isoform is expressed in a number of tissues including liver, heart and lungs. The short isoform is expressed in skin and cartilage- containing tissues such as tail and front paw. No expression is found in brain. {ECO:0000269|PubMed:11165938}. |
Recombinant Mouse ECM-1, CF - 4428-EC-050 from R&D Systems
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Recombinant Mouse Ecm1, His-tagged - Ecm1-363M from Creative Biomart
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Recombinant Mouse Ecm1, His tagged - Ecm1-4027M from Creative Biomart
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ECM1 - PN201517 from Elabscience
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Mouse ECM1 Protein (His Tag) - 50331-M08H-50 from Sino Biological
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Recombinant Extracellular Matrix Protein 1 (ECM1) - RPC450Mu01 from Cloud-clone
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Recombinant Extracellular Matrix Protein 1 (ECM1) - RPC450Mu02 from Cloud-clone
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Recombinant Mouse Extracellular matrix protein 1(Ecm1) - CSB-YP007383MO CSB-EP007383MO CSB-BP007383MO CSB-MP007383MO from Cusabio
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Recombinant Mouse ECM1 Protein, CF - 4428-EC from R&D Systems
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ECM, Peptide - MBS843818 from MyBioSource
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Recombinant Mouse ECM1 Protein (His tag) - PKSM040729 from Elabscience
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ECM1 Recombinant Protein (OPCD02841) - OPCD02841 from Aviva Systems Biology
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Mouse ECM1 Protein (His Tag) - 50331-M08H from ABclonal
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ECM1, Recombinant Protein - MBS2547029 from MyBioSource
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Extracellular matrix protein 1 (Ecm1), Recombinant Protein - MBS1403334 from MyBioSource
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