Gene Symbol | Ecm1 |
---|---|
Entrez Gene | 13601 |
Alt Symbol | AI663821, p85 |
Species | Mouse |
Gene Type | protein-coding |
Description | extracellular matrix protein 1 |
Other Description | secretory component p85 |
Swissprots | Q3U5Q5 Q61508 |
Accessions | AAD13396 AAD13397 EDL38831 EDL38832 Q61508 AK153009 BAE31648 AK153471 BAE32022 AK159334 BAE34999 AK169939 BAE41471 BC138693 AAI38694 BC145381 AAI45382 BY224903 L33416 AAA37535 XM_006500984 XP_006501047 XM_006500985 XP_006501048 XM_011240008 XP_011238310 XM_011240009 XP_011238311 NM_001252653 NP_001239582 NM_007899 NP_031925 |
Function | Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix. |
Tissue Specificity | Expressed in the connective tissues surronding developing long bones, but not in the cartilage. The long isoform is expressed in a number of tissues including liver, heart and lungs. The short isoform is expressed in skin and cartilage- containing tissues such as tail and front paw. No expression is found in brain. {ECO:0000269|PubMed:11165938}. |
ECM1 CRISPR/Cas9 KO Plasmid (m) - sc-420098 from Santa Cruz Biotechnology
|
||||||||
ECM1 HDR Plasmid (m) - sc-420098-HDR from Santa Cruz Biotechnology
|
||||||||
ECM1 Double Nickase Plasmid (m) - sc-420098-NIC from Santa Cruz Biotechnology
|
||||||||
ECM1 Double Nickase Plasmid (m2) - sc-420098-NIC-2 from Santa Cruz Biotechnology
|
||||||||
ECM1 CRISPR Activation Plasmid (m) - sc-420098-ACT from Santa Cruz Biotechnology
|
||||||||
ECM1 CRISPR Activation Plasmid (m2) - sc-420098-ACT-2 from Santa Cruz Biotechnology
|
||||||||
ECM1 Lentiviral Activation Particles (m) - sc-420098-LAC from Santa Cruz Biotechnology
|
||||||||
ECM1 Lentiviral Activation Particles (m2) - sc-420098-LAC-2 from Santa Cruz Biotechnology
|
||||||||
ECM1 siRNA (m) - sc-62256 from Santa Cruz Biotechnology
|
||||||||
ECM1 shRNA Plasmid (m) - sc-62256-SH from Santa Cruz Biotechnology
|
||||||||
ECM1 shRNA (m) Lentiviral Particles - sc-62256-V from Santa Cruz Biotechnology
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN30416 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND30416 from Sigma-Aldrich
|
||||||||
ECM1 siRNA (Mouse) - CRM1122 from Cohesion Biosciences
|
||||||||
ECM1 - MBS8213765 from MyBioSource
|
||||||||
shRNA set against Mouse ECM1 (NM_007899.2) - SHH282977 from Creative biogene
|
||||||||
Mouse ECM1 siRNA - orb280598 from Biorbyt
|
||||||||
ECM1 shRNA Plasmid (Mouse) - CHM1122 from Cohesion Biosciences
|
||||||||