| Gene Symbol |
TREML1
|
| Entrez Gene |
340205
|
| Alt Symbol |
GLTL1825, PRO3438, TLT-1, TLT1, dJ238O23.3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
triggering receptor expressed on myeloid cells-like 1
|
| Other Description |
trem-like transcript 1 protein|triggering receptor expressed on myeloid cells-like protein 1
|
| Swissprots |
Q8IWY1 Q86YW5 Q8IWY2 Q496B3
|
| Accessions |
EAX04029 EAX04030 EAX04031 Q86YW5 AF508193 AAO37827 AF534822 AAO15020 AF534823 AAO15021 AY358357 AAQ88723 BC100944 AAI00945 BC100945 AAI00946 BC100946 AAI00947 BQ023322 DW009745 NM_001271807 NP_001258736 NM_001271808 NP_001258737 NM_178174 NP_835468
|
| Function |
Cell surface receptor that may play a role in the innate and adaptive immune response. {ECO:0000269|PubMed:15128762}.
|
| Subcellular Location |
Cell membrane; Single-pass type I membrane protein. Cytoplasm. Note=Sequestered in cytoplasmic vesicles in resting platelets. Transported to the cell surface after stimulation by thrombin. Soluble fragments can be released into the serum by proteolysis.
|
| Tissue Specificity |
Detected in platelets, monocytic leukemia and in T-cell leukemia. {ECO:0000269|PubMed:12645956, ECO:0000269|PubMed:15100151, ECO:0000269|PubMed:15128762, ECO:0000269|PubMed:16505478}.
|
![Western Blot: TREML1 Overexpression Lysate (Adult Normal) [NBL1-17265] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TREML1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/19319_TREML1%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-17265-img0002.jpg)