Gene Symbol | TREML1 |
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Entrez Gene | 340205 |
Alt Symbol | GLTL1825, PRO3438, TLT-1, TLT1, dJ238O23.3 |
Species | Human |
Gene Type | protein-coding |
Description | triggering receptor expressed on myeloid cells-like 1 |
Other Description | trem-like transcript 1 protein|triggering receptor expressed on myeloid cells-like protein 1 |
Swissprots | Q8IWY1 Q86YW5 Q8IWY2 Q496B3 |
Accessions | EAX04029 EAX04030 EAX04031 Q86YW5 AF508193 AAO37827 AF534822 AAO15020 AF534823 AAO15021 AY358357 AAQ88723 BC100944 AAI00945 BC100945 AAI00946 BC100946 AAI00947 BQ023322 DW009745 NM_001271807 NP_001258736 NM_001271808 NP_001258737 NM_178174 NP_835468 |
Function | Cell surface receptor that may play a role in the innate and adaptive immune response. {ECO:0000269|PubMed:15128762}. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. Cytoplasm. Note=Sequestered in cytoplasmic vesicles in resting platelets. Transported to the cell surface after stimulation by thrombin. Soluble fragments can be released into the serum by proteolysis. |
Tissue Specificity | Detected in platelets, monocytic leukemia and in T-cell leukemia. {ECO:0000269|PubMed:12645956, ECO:0000269|PubMed:15100151, ECO:0000269|PubMed:15128762, ECO:0000269|PubMed:16505478}. |
TREML1 CRISPR/Cas9 KO Plasmid (h) - sc-409523 from Santa Cruz Biotechnology
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TREML1 HDR Plasmid (h) - sc-409523-HDR from Santa Cruz Biotechnology
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TREML1 Double Nickase Plasmid (h) - sc-409523-NIC from Santa Cruz Biotechnology
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TREML1 Double Nickase Plasmid (h2) - sc-409523-NIC-2 from Santa Cruz Biotechnology
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TREML1 CRISPR Activation Plasmid (h) - sc-409523-ACT from Santa Cruz Biotechnology
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TREML1 CRISPR Activation Plasmid (h2) - sc-409523-ACT-2 from Santa Cruz Biotechnology
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TREML1 Lentiviral Activation Particles (h) - sc-409523-LAC from Santa Cruz Biotechnology
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TREML1 Lentiviral Activation Particles (h2) - sc-409523-LAC-2 from Santa Cruz Biotechnology
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TREML1 siRNA (h) - sc-95479 from Santa Cruz Biotechnology
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TREML1 shRNA Plasmid (h) - sc-95479-SH from Santa Cruz Biotechnology
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TREML1 shRNA (h) Lentiviral Particles - sc-95479-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU121981 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21939 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21939 from Sigma-Aldrich
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TREML1 siRNA (Human) - CRJ7332 from Cohesion Biosciences
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TREML1 - MBS8211083 from MyBioSource
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shRNA set against Human TREML1 (NM_178174.2) - SHH434176 from Creative biogene
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shRNA set against Human TREML1(NM_178174.2) - SHL092424 from Creative biogene
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TREML1 shRNA Plasmid (Human) - CHJ7332 from Cohesion Biosciences
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TREML1 miRNA 3'UTR clone - MiUTR1H-10706 from Creative biogene
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