| Gene Symbol |
DPH5
|
| Entrez Gene |
51611
|
| Alt Symbol |
AD-018, CGI-30, HSPC143, NPD015
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
diphthamide biosynthesis 5
|
| Other Description |
DPH5 homolog|diphthamide biosynthesis methyltransferase|diphthine synthase|protein x 0011
|
| Swissprots |
Q9P017 Q9Y319 D3DT62 Q9H2P9 Q9P0I4 A8JZY6
|
| Accessions |
EAW72932 EAW72933 EAW72934 EAW72935 EAW72936 EAW72937 EAW72938 EAW72939 EAW72940 EAW72941 Q9H2P9 AF132964 AAD27739 AF157319 AAF67485 AF161492 AAF29107 AF248965 AAG44563 AK125485 BAG54203 AK225469 AK225707 AK225951 AK289351 BAF82040 AK298181 BAG60452 BC009620 AAH09620 BC034669 BC053857 AAH53857 BI907367 BM808505 CK002046 DA133565 XM_005270938 XP_005270995 XM_005270939 XP_005270996 XM_005270941 XP_005270998 XM_006710683 XP_006710746 XM_011541569 XP_011539871 XM_011541570 XP_011539872 NM_001077394 NP_001070862 NM_001077395 NP_001070863 NM_015958 NP_057042
|
| Function |
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EEF2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. {ECO:0000269|PubMed:23486472}.
|