Gene Symbol | DPH5 |
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Entrez Gene | 51611 |
Alt Symbol | AD-018, CGI-30, HSPC143, NPD015 |
Species | Human |
Gene Type | protein-coding |
Description | diphthamide biosynthesis 5 |
Other Description | DPH5 homolog|diphthamide biosynthesis methyltransferase|diphthine synthase|protein x 0011 |
Swissprots | Q9P017 Q9Y319 D3DT62 Q9H2P9 Q9P0I4 A8JZY6 |
Accessions | EAW72932 EAW72933 EAW72934 EAW72935 EAW72936 EAW72937 EAW72938 EAW72939 EAW72940 EAW72941 Q9H2P9 AF132964 AAD27739 AF157319 AAF67485 AF161492 AAF29107 AF248965 AAG44563 AK125485 BAG54203 AK225469 AK225707 AK225951 AK289351 BAF82040 AK298181 BAG60452 BC009620 AAH09620 BC034669 BC053857 AAH53857 BI907367 BM808505 CK002046 DA133565 XM_005270938 XP_005270995 XM_005270939 XP_005270996 XM_005270941 XP_005270998 XM_006710683 XP_006710746 XM_011541569 XP_011539871 XM_011541570 XP_011539872 NM_001077394 NP_001070862 NM_001077395 NP_001070863 NM_015958 NP_057042 |
Function | S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EEF2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. {ECO:0000269|PubMed:23486472}. |
DPH5 CRISPR/Cas9 KO Plasmid (h) - sc-412225 from Santa Cruz Biotechnology
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DPH5 HDR Plasmid (h) - sc-412225-HDR from Santa Cruz Biotechnology
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DPH5 Double Nickase Plasmid (h) - sc-412225-NIC from Santa Cruz Biotechnology
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DPH5 Double Nickase Plasmid (h2) - sc-412225-NIC-2 from Santa Cruz Biotechnology
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DPH5 CRISPR Activation Plasmid (h) - sc-412225-ACT from Santa Cruz Biotechnology
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DPH5 CRISPR Activation Plasmid (h2) - sc-412225-ACT-2 from Santa Cruz Biotechnology
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DPH5 Lentiviral Activation Particles (h) - sc-412225-LAC from Santa Cruz Biotechnology
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DPH5 Lentiviral Activation Particles (h2) - sc-412225-LAC-2 from Santa Cruz Biotechnology
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DPH5 siRNA (h) - sc-88546 from Santa Cruz Biotechnology
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DPH5 shRNA Plasmid (h) - sc-88546-SH from Santa Cruz Biotechnology
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DPH5 shRNA (h) Lentiviral Particles - sc-88546-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU124841 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7454 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7454 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06402 from Sigma-Aldrich
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DPH5 siRNA (Human) - CRH9859 from Cohesion Biosciences
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DPH5 - MBS8222716 from MyBioSource
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shRNA set against Human DPH5 (NM_015958.2) - SHH280593 from Creative biogene
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shRNA set against Human DPH5(NM_001077395.1) - SHG209089 from Creative biogene
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shRNA set against Human DPH5(NM_001077394.1) - SHG209143 from Creative biogene
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Human DPH5 siRNA - orb270361 from Biorbyt
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DPH5 shRNA Plasmid (Human) - CHH9859 from Cohesion Biosciences
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DPH5 miRNA 3'UTR clone - MiUTR1H-02968 from Creative biogene
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DPH5 miRNA 3'UTR clone - MiUTR1H-02969 from Creative biogene
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DPH5 miRNA 3'UTR clone - MiUTR3H-11638 from Creative biogene
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