| Gene Symbol |
NDUFS4
|
| Entrez Gene |
4724
|
| Alt Symbol |
AQDQ, CI-18
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
|
| Other Description |
CI-18 kDa|CI-AQDQ|NADH dehydrogenase (ubiquinone) iron-sulfur protein 4|NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial|NADH-coenzyme Q reductase, 18-KD|NADH-ubiquinone oxidoreductase 18 kDa subunit|complex I 18kDa subunit|complex I-18 kDa|complex I-AQDQ|mitochondrial respiratory chain complex I (18-KD subunit)
|
| Swissprots |
O43181 Q9BS69
|
| Accessions |
EAW54884 O43181 AF020351 AAB87865 AI001139 AK307973 BC005270 AAH05270 BU954271 DB489661 HQ448017 ADQ32498 XM_005248525 XP_005248582 XM_011543414 XP_011541716 XM_011543415 XP_011541717 NM_002495 NP_002486
|
| Function |
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
|
| Subcellular Location |
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
|
| Top Pathways |
Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation
|