Gene Symbol | NDUFS4 |
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Entrez Gene | 4724 |
Alt Symbol | AQDQ, CI-18 |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) |
Other Description | CI-18 kDa|CI-AQDQ|NADH dehydrogenase (ubiquinone) iron-sulfur protein 4|NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial|NADH-coenzyme Q reductase, 18-KD|NADH-ubiquinone oxidoreductase 18 kDa subunit|complex I 18kDa subunit|complex I-18 kDa|complex I-AQDQ|mitochondrial respiratory chain complex I (18-KD subunit) |
Swissprots | O43181 Q9BS69 |
Accessions | EAW54884 O43181 AF020351 AAB87865 AI001139 AK307973 BC005270 AAH05270 BU954271 DB489661 HQ448017 ADQ32498 XM_005248525 XP_005248582 XM_011543414 XP_011541716 XM_011543415 XP_011541717 NM_002495 NP_002486 |
Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Subcellular Location | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFS4 CRISPR/Cas9 KO Plasmid (h) - sc-405184 from Santa Cruz Biotechnology
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NDUFS4 HDR Plasmid (h) - sc-405184-HDR from Santa Cruz Biotechnology
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NDUFS4 Double Nickase Plasmid (h) - sc-405184-NIC from Santa Cruz Biotechnology
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NDUFS4 Double Nickase Plasmid (h2) - sc-405184-NIC-2 from Santa Cruz Biotechnology
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NDUFS4 CRISPR Activation Plasmid (h) - sc-405184-ACT from Santa Cruz Biotechnology
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NDUFS4 CRISPR Activation Plasmid (h2) - sc-405184-ACT-2 from Santa Cruz Biotechnology
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NDUFS4 Lentiviral Activation Particles (h) - sc-405184-LAC from Santa Cruz Biotechnology
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NDUFS4 Lentiviral Activation Particles (h2) - sc-405184-LAC-2 from Santa Cruz Biotechnology
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NDUFS4 siRNA (h) - sc-75892 from Santa Cruz Biotechnology
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NDUFS4 shRNA Plasmid (h) - sc-75892-SH from Santa Cruz Biotechnology
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NDUFS4 shRNA (h) Lentiviral Particles - sc-75892-V from Santa Cruz Biotechnology
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Ndufs4 RNAi - H00004724-R01V from Novus Biologicals
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Ndufs4 RNAi - H00004724-R01 from Novus Biologicals
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MISSION® esiRNA - EHU015281 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15169 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15169 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00674 from Sigma-Aldrich
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NDUFS4 siRNA (Human) - CRH3137 from Cohesion Biosciences
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Human NDUFS4 siRNA - orb263639 from Biorbyt
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NDUFS4 shRNA Plasmid (Human) - CHH3137 from Cohesion Biosciences
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