TRIM36

Gene Symbol TRIM36
Entrez Gene 55521
Alt Symbol HAPRIN, RBCC728, RNF98
Species Human
Gene Type protein-coding
Description tripartite motif containing 36
Other Description E3 ubiquitin-protein ligase TRIM36|RING finger protein 98|tripartite motif protein 36|tripartite motif-containing 36|tripartite motif-containing protein 36|zinc-binding protein Rbcc728
Swissprots B7Z3V4 E9PFI8 B7ZAV7 A6NDD0 A1L3Z1 Q0P5Z9 Q9NQ86
Accessions EAW48971 EAW48972 Q9NQ86 AB196558 BAD99605 AI142389 AJ272269 CAB94831 AK058179 AK125426 AK296389 BAH12340 AK316422 BAH14793 BC017346 BC045164 AAH45164 BC046096 AAH46096 BC130334 AAI30335 BF592910 DC397736 XM_005272034 XP_005272091 XM_011543508 XP_011541810 NM_001017397 NP_001017397 NM_001017398 NP_001017398 NM_001300752 NP_001287681 NM_001300759 NP_001287688 NM_018700 NP_061170
Function E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Involved in chromosome segregation and cell cycle regulation. May play a role in the acrosome reaction and fertilization (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Found in the acrosomal region of elongated spermatids and mature sperm. {ECO:0000250}.
Tissue Specificity Highly expressed in testis, prostate and brain. Weakly expressed in kidney, lung and heart. {ECO:0000269|PubMed:15145053}.

Panoply™ Human TRIM36 Knockdown Stable Cell Line - CSC-DC016588 from Creative biogene

Category Cell Line
Species Human
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