| Gene Symbol |
TRIM36
|
| Entrez Gene |
55521
|
| Alt Symbol |
HAPRIN, RBCC728, RNF98
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tripartite motif containing 36
|
| Other Description |
E3 ubiquitin-protein ligase TRIM36|RING finger protein 98|tripartite motif protein 36|tripartite motif-containing 36|tripartite motif-containing protein 36|zinc-binding protein Rbcc728
|
| Swissprots |
B7Z3V4 E9PFI8 B7ZAV7 A6NDD0 A1L3Z1 Q0P5Z9 Q9NQ86
|
| Accessions |
EAW48971 EAW48972 Q9NQ86 AB196558 BAD99605 AI142389 AJ272269 CAB94831 AK058179 AK125426 AK296389 BAH12340 AK316422 BAH14793 BC017346 BC045164 AAH45164 BC046096 AAH46096 BC130334 AAI30335 BF592910 DC397736 XM_005272034 XP_005272091 XM_011543508 XP_011541810 NM_001017397 NP_001017397 NM_001017398 NP_001017398 NM_001300752 NP_001287681 NM_001300759 NP_001287688 NM_018700 NP_061170
|
| Function |
E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Involved in chromosome segregation and cell cycle regulation. May play a role in the acrosome reaction and fertilization (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Found in the acrosomal region of elongated spermatids and mature sperm. {ECO:0000250}.
|
| Tissue Specificity |
Highly expressed in testis, prostate and brain. Weakly expressed in kidney, lung and heart. {ECO:0000269|PubMed:15145053}.
|