TRIM36
| Gene Symbol | TRIM36 |
|---|---|
| Entrez Gene | 55521 |
| Alt Symbol | HAPRIN, RBCC728, RNF98 |
| Species | Human |
| Gene Type | protein-coding |
| Description | tripartite motif containing 36 |
| Other Description | E3 ubiquitin-protein ligase TRIM36|RING finger protein 98|tripartite motif protein 36|tripartite motif-containing 36|tripartite motif-containing protein 36|zinc-binding protein Rbcc728 |
| Swissprots | B7Z3V4 E9PFI8 B7ZAV7 A6NDD0 A1L3Z1 Q0P5Z9 Q9NQ86 |
| Accessions | EAW48971 EAW48972 Q9NQ86 AB196558 BAD99605 AI142389 AJ272269 CAB94831 AK058179 AK125426 AK296389 BAH12340 AK316422 BAH14793 BC017346 BC045164 AAH45164 BC046096 AAH46096 BC130334 AAI30335 BF592910 DC397736 XM_005272034 XP_005272091 XM_011543508 XP_011541810 NM_001017397 NP_001017397 NM_001017398 NP_001017398 NM_001300752 NP_001287681 NM_001300759 NP_001287688 NM_018700 NP_061170 |
| Function | E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Involved in chromosome segregation and cell cycle regulation. May play a role in the acrosome reaction and fertilization (By similarity). {ECO:0000250}. |
| Subcellular Location | Cytoplasm {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Found in the acrosomal region of elongated spermatids and mature sperm. {ECO:0000250}. |
| Tissue Specificity | Highly expressed in testis, prostate and brain. Weakly expressed in kidney, lung and heart. {ECO:0000269|PubMed:15145053}. |
TRIM36 CRISPR/Cas9 KO Plasmid (h) - sc-412543 from Santa Cruz Biotechnology
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TRIM36 HDR Plasmid (h) - sc-412543-HDR from Santa Cruz Biotechnology
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TRIM36 Double Nickase Plasmid (h) - sc-412543-NIC from Santa Cruz Biotechnology
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TRIM36 Double Nickase Plasmid (h2) - sc-412543-NIC-2 from Santa Cruz Biotechnology
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TRIM36 CRISPR Activation Plasmid (h) - sc-412543-ACT from Santa Cruz Biotechnology
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TRIM36 CRISPR Activation Plasmid (h2) - sc-412543-ACT-2 from Santa Cruz Biotechnology
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TRIM36 Lentiviral Activation Particles (h) - sc-412543-LAC from Santa Cruz Biotechnology
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TRIM36 Lentiviral Activation Particles (h2) - sc-412543-LAC-2 from Santa Cruz Biotechnology
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TRIM36 siRNA (h) - sc-91989 from Santa Cruz Biotechnology
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TRIM36 shRNA Plasmid (h) - sc-91989-SH from Santa Cruz Biotechnology
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TRIM36 shRNA (h) Lentiviral Particles - sc-91989-V from Santa Cruz Biotechnology
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RNF98 RNAi - H00055521-R01 from Novus Biologicals
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RNF98 RNAi - H00055521-R03 from Novus Biologicals
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RNF98 RNAi - H00055521-R02 from Novus Biologicals
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MISSION® esiRNA - EHU129581 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21974 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21974 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10350 from Sigma-Aldrich
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TRIM36 siRNA (Human) - CRJ0724 from Cohesion Biosciences
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TRIM36 - MBS8202655 from MyBioSource
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shRNA set against Human Trim36 (NM_018700.3) - SHH434664 from Creative biogene
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shRNA set against Human TRIM36(NM_018700.3) - SHL094332 from Creative biogene
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shRNA set against Human TRIM36(NM_001017397.1) - SHL094350 from Creative biogene
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shRNA set against Human TRIM36(NM_001017398.1) - SHL094358 from Creative biogene
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shRNA set against Human TRIM36(NM_001017397.1) - SHL094359 from Creative biogene
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