| Gene Symbol |
AMDHD2
|
| Entrez Gene |
51005
|
| Alt Symbol |
CGI-14
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
amidohydrolase domain containing 2
|
| Other Description |
amidohydrolase domain-containing protein 2|glcNAc 6-P deacetylase|putative N-acetylglucosamine-6-phosphate deacetylase
|
| Swissprots |
Q8WV54 Q9Y303 B4DL77
|
| Accessions |
CBG19170 CBV32525 EAW85498 EAW85499 EAW85500 Q9Y303 AB209351 BAD92588 AF132948 AAD27723 AK296877 BAG59439 AK300747 BAG62416 BC018734 AAH18734 CN362870 NM_001145815 NP_001139287 NM_015944 NP_057028
|
| Function |
Hydrolyzes the N-glycolyl group from N- glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N- glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. {ECO:0000269|PubMed:22692205}.
|
| Top Pathways |
Amino sugar and nucleotide sugar metabolism
|