Gene Symbol | AMDHD2 |
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Entrez Gene | 51005 |
Alt Symbol | CGI-14 |
Species | Human |
Gene Type | protein-coding |
Description | amidohydrolase domain containing 2 |
Other Description | amidohydrolase domain-containing protein 2|glcNAc 6-P deacetylase|putative N-acetylglucosamine-6-phosphate deacetylase |
Swissprots | Q8WV54 Q9Y303 B4DL77 |
Accessions | CBG19170 CBV32525 EAW85498 EAW85499 EAW85500 Q9Y303 AB209351 BAD92588 AF132948 AAD27723 AK296877 BAG59439 AK300747 BAG62416 BC018734 AAH18734 CN362870 NM_001145815 NP_001139287 NM_015944 NP_057028 |
Function | Hydrolyzes the N-glycolyl group from N- glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N- glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. {ECO:0000269|PubMed:22692205}. |
Top Pathways | Amino sugar and nucleotide sugar metabolism |
AMDHD2 CRISPR/Cas9 KO Plasmid (h) - sc-412087 from Santa Cruz Biotechnology
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AMDHD2 HDR Plasmid (h) - sc-412087-HDR from Santa Cruz Biotechnology
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AMDHD2 Double Nickase Plasmid (h) - sc-412087-NIC from Santa Cruz Biotechnology
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AMDHD2 Double Nickase Plasmid (h2) - sc-412087-NIC-2 from Santa Cruz Biotechnology
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AMDHD2 CRISPR Activation Plasmid (h) - sc-412087-ACT from Santa Cruz Biotechnology
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AMDHD2 CRISPR Activation Plasmid (h2) - sc-412087-ACT-2 from Santa Cruz Biotechnology
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AMDHD2 Lentiviral Activation Particles (h) - sc-412087-LAC from Santa Cruz Biotechnology
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AMDHD2 Lentiviral Activation Particles (h2) - sc-412087-LAC-2 from Santa Cruz Biotechnology
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AMDHD2 siRNA (h) - sc-93453 from Santa Cruz Biotechnology
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AMDHD2 shRNA Plasmid (h) - sc-93453-SH from Santa Cruz Biotechnology
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AMDHD2 shRNA (h) Lentiviral Particles - sc-93453-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU146531 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3107 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3107 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00317 from Sigma-Aldrich
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AMDHD2 siRNA (Human) - CRH9447 from Cohesion Biosciences
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AMDHD2 - MBS8238890 from MyBioSource
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shRNA set against Human AMDHD2 (NM_015944.3) - SHH235698 from Creative biogene
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Human AMDHD2 siRNA - orb269949 from Biorbyt
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AMDHD2 shRNA Plasmid (Human) - CHH9447 from Cohesion Biosciences
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AMDHD2 miRNA 3'UTR clone - MiUTR3H-13555 from Creative biogene
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AMDHD2 miRNA 3'UTR clone - MiUTR3H-13556 from Creative biogene
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