Gene Symbol | ST6GAL2 |
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Entrez Gene | 84620 |
Alt Symbol | SIAT2, ST6GalII |
Species | Human |
Gene Type | protein-coding |
Description | ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 |
Other Description | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 2|alpha 2,6-ST 2|beta-galactoside alpha-2,6-sialyltransferase 2|beta-galactoside alpha-2,6-sialyltransferase II|sialyltransferase 2 (monosialoganglioside sialyltransferase) |
Swissprots | D3DVK3 Q96HE4 Q8IUG7 Q96JF0 Q86Y44 Q53QP4 |
Accessions | AAY15022 CAS91680 EAX01742 EAX01743 Q96JF0 AB058780 BAB47506 AB059555 BAC24793 AJ512141 CAD54408 AK055273 AK095049 AK095653 AK307784 BC008680 AAH08680 BQ016989 CN365495 DA176100 FJ433883 ACQ63561 FJ433884 ACQ63562 FJ433885 ACQ63563 JF432175 ADZ15392 XM_006712801 XP_006712864 XM_006712802 XP_006712865 XM_011511999 XP_011510301 XM_011512000 XP_011510302 XM_011512001 XP_011510303 XM_011512002 XP_011510304 XM_011512003 XP_011510305 XR_923046 NM_001142351 NP_001135823 NM_001142352 NP_001135824 NM_032528 NP_115917 |
Function | Transfers sialic acid from the donor of substrate CMP- sialic acid to galactose containing acceptor substrates. Has alpha-2,6-sialyltransferase activity toward oligosaccharides that have the Gal-beta-1,4-GlcNAc sequence at the non-reducing end of their carbohydrate groups, but it has weak or no activities toward glycoproteins and glycolipids. |
Subcellular Location | Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Tissue Specificity | Weakly expressed in some tissues, such as small intestine, colon and fetal brain. {ECO:0000269|PubMed:12235148, ECO:0000269|PubMed:12603328}. |
Top Pathways | N-Glycan biosynthesis, Other types of O-glycan biosynthesis |
ST6GAL2 (C-16) - sc-324364 from Santa Cruz Biotechnology
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ST6GAL2 (S-16) - sc-324363 from Santa Cruz Biotechnology
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Anti-ST6GAL2 antibody - ab69276 from Abcam
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Anti-ST6GAL2 antibody - C-terminal - ab174506 from Abcam
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Anti-ST6GAL2 Antibody (aa483-509, AP) - LS-C241289 from LifeSpan Bioscience
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Anti-ST6GAL2 Antibody (aa483-509, APC) - LS-C241291 from LifeSpan Bioscience
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Anti-ST6GAL2 Antibody (aa483-509, Biotin) - LS-C241292 from LifeSpan Bioscience
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Anti-ST6GAL2 Antibody (aa483-509, FITC) - LS-C241293 from LifeSpan Bioscience
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Anti-ST6GAL2 Antibody (aa483-509, Azide-free, HRP) - LS-C248258 from LifeSpan Bioscience
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Anti-ST6GAL2 Antibody (aa483-509, PE) - LS-C241294 from LifeSpan Bioscience
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Anti-ST6GAL2 Antibody (aa483-509) - LS-C325413 from LifeSpan Bioscience
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Anti-ST6GAL2 Antibody (aa286-335) - LS-C135240 from LifeSpan Bioscience
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Anti-ST6GAL2 Antibody (aa483-509) - LS-C156152 from LifeSpan Bioscience
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ST6 Gal Sialyltransferase 2/ST6GAL2 Antibody - AF7747 from Novus Biologicals
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ST6 Gal Sialyltransferase 2/ST6GAL2 Antibody - NBP1-81364 from Novus Biologicals
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ST6 Gal Sialyltransferase 2/ST6GAL2 Antibody - H00084620-B01P from Novus Biologicals
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ST6GAL2-AntibodyC-term - AP19472b from Abgent, a WuXi AppTec company
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ST6GAL2 Antibody - C-terminal region (OAAB15035) - OAAB15035 from Aviva Systems Biology
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Human ST6 Gal Sialyltransferase 2/ST6GAL2 Antibody - AF7747 from R&D Systems
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Human ST6GAL2 Affinity Purified Polyclonal Ab, Sheep IgG - AF7747-SP from R&D Systems
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St6gal2 antibody - 70R-8851 from Fitzgerald
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ST6GAL2 Antibody - abx031033 from Abbexa
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ST6GAL2 antibody - H00084620-B01P from Acris Antibodies
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Rabbit Anti-Human ST6GAL2(C-term) - 102-14289 from RayBiotech
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ST6GAL2 antibody (C-term) - STJ47532 from St John's Laboratory Ltd
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