| Gene Symbol |
TST
|
| Entrez Gene |
7263
|
| Alt Symbol |
RDS
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
thiosulfate sulfurtransferase (rhodanese)
|
| Other Description |
thiosulfate sulfurtransferase
|
| Swissprots |
Q16762 Q6IB06 B3KRM1
|
| Accessions |
EAW60132 Q16762 AI869664 AK000862 AK091874 BAG52433 AK223521 BAD97241 AK301300 BAG62856 AW070418 BC010148 AAH10148 BI820468 BQ231617 CR456598 CAG30484 CR456998 CAG33279 CU013198 CAK54629 CU013486 CAK54928 D87292 BAA13327 NM_001270483 NP_001257412 NM_003312 NP_003303
|
| Function |
Formation of iron-sulfur complexes, cyanide detoxification or modification of sulfur-containing enzymes. Other thiol compounds, besides cyanide, can act as sulfur ion acceptors. Also has weak mercaptopyruvate sulfurtransferase (MST) activity (By similarity). Together with MRPL18, acts as a mitochondrial import factor for the cytosolic 5S rRNA. Only the nascent unfolded cytoplasmic form is able to bind to the 5S rRNA. {ECO:0000250, ECO:0000269|PubMed:20663881, ECO:0000269|PubMed:21685364}.
|
| Subcellular Location |
Mitochondrion matrix.
|
| Top Pathways |
Sulfur metabolism, Cysteine and methionine metabolism, Sulfur relay system
|