Gene Symbol | TST |
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Entrez Gene | 7263 |
Alt Symbol | RDS |
Species | Human |
Gene Type | protein-coding |
Description | thiosulfate sulfurtransferase (rhodanese) |
Other Description | thiosulfate sulfurtransferase |
Swissprots | Q16762 Q6IB06 B3KRM1 |
Accessions | EAW60132 Q16762 AI869664 AK000862 AK091874 BAG52433 AK223521 BAD97241 AK301300 BAG62856 AW070418 BC010148 AAH10148 BI820468 BQ231617 CR456598 CAG30484 CR456998 CAG33279 CU013198 CAK54629 CU013486 CAK54928 D87292 BAA13327 NM_001270483 NP_001257412 NM_003312 NP_003303 |
Function | Formation of iron-sulfur complexes, cyanide detoxification or modification of sulfur-containing enzymes. Other thiol compounds, besides cyanide, can act as sulfur ion acceptors. Also has weak mercaptopyruvate sulfurtransferase (MST) activity (By similarity). Together with MRPL18, acts as a mitochondrial import factor for the cytosolic 5S rRNA. Only the nascent unfolded cytoplasmic form is able to bind to the 5S rRNA. {ECO:0000250, ECO:0000269|PubMed:20663881, ECO:0000269|PubMed:21685364}. |
Subcellular Location | Mitochondrion matrix. |
Top Pathways | Sulfur metabolism, Cysteine and methionine metabolism, Sulfur relay system |
Rhodanese CRISPR/Cas9 KO Plasmid (h) - sc-405813 from Santa Cruz Biotechnology
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Rhodanese HDR Plasmid (h) - sc-405813-HDR from Santa Cruz Biotechnology
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Rhodanese Double Nickase Plasmid (h) - sc-405813-NIC from Santa Cruz Biotechnology
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Rhodanese Double Nickase Plasmid (h2) - sc-405813-NIC-2 from Santa Cruz Biotechnology
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Rhodanese CRISPR Activation Plasmid (h) - sc-405813-ACT from Santa Cruz Biotechnology
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Rhodanese CRISPR Activation Plasmid (h2) - sc-405813-ACT-2 from Santa Cruz Biotechnology
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Rhodanese Lentiviral Activation Particles (h) - sc-405813-LAC from Santa Cruz Biotechnology
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Rhodanese Lentiviral Activation Particles (h2) - sc-405813-LAC-2 from Santa Cruz Biotechnology
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Rhodanese siRNA (h) - sc-36418 from Santa Cruz Biotechnology
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Rhodanese shRNA Plasmid (h) - sc-36418-SH from Santa Cruz Biotechnology
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Rhodanese shRNA (h) Lentiviral Particles - sc-36418-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU133251 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2150 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2150 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00193 from Sigma-Aldrich
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TST siRNA (Human) - CRH4963 from Cohesion Biosciences
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TST - MBS8228256 from MyBioSource
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shRNA set against Human TST (NM_003312.5) - SHH436676 from Creative biogene
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TST shRNA Plasmid (Human) - CHH4963 from Cohesion Biosciences
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TST miRNA 3'UTR clone - MiUTR3H-02038 from Creative biogene
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