| Gene Symbol |
RGMB
|
| Entrez Gene |
285704
|
| Alt Symbol |
DRAGON
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
repulsive guidance molecule family member b
|
| Other Description |
DRG11-responsive axonal guidance and outgrowth of neurite|RGM domain family member B|RGM domain family, member B|repulsive guidance molecule B
|
| Swissprots |
Q8NC92 D6R9A0 Q6NW40
|
| Accessions |
CAF86831 EAW96093 EAW96094 EAW96095 Q6NW40 AK054622 AK074887 BAC11268 AK125284 BC020513 BC044231 BC067736 AAH67736 BG251558 BI763873 XM_005271966 XP_005272023 XM_011543345 XP_011541647 XM_011543346 XP_011541648 XM_011543347 XP_011541649 NM_173670 NM_001012761 NP_001012779
|
| Function |
Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth. {ECO:0000250, ECO:0000269|PubMed:19324014}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}. Membrane raft {ECO:0000250}.
|