Gene Symbol | RGMB |
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Entrez Gene | 285704 |
Alt Symbol | DRAGON |
Species | Human |
Gene Type | protein-coding |
Description | repulsive guidance molecule family member b |
Other Description | DRG11-responsive axonal guidance and outgrowth of neurite|RGM domain family member B|RGM domain family, member B|repulsive guidance molecule B |
Swissprots | Q8NC92 D6R9A0 Q6NW40 |
Accessions | CAF86831 EAW96093 EAW96094 EAW96095 Q6NW40 AK054622 AK074887 BAC11268 AK125284 BC020513 BC044231 BC067736 AAH67736 BG251558 BI763873 XM_005271966 XP_005272023 XM_011543345 XP_011541647 XM_011543346 XP_011541648 XM_011543347 XP_011541649 NM_173670 NM_001012761 NP_001012779 |
Function | Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth. {ECO:0000250, ECO:0000269|PubMed:19324014}. |
Subcellular Location | Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}. Membrane raft {ECO:0000250}. |
RGMb CRISPR/Cas9 KO Plasmid (h) - sc-406151 from Santa Cruz Biotechnology
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RGMb HDR Plasmid (h) - sc-406151-HDR from Santa Cruz Biotechnology
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RGMb Double Nickase Plasmid (h) - sc-406151-NIC from Santa Cruz Biotechnology
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RGMb Double Nickase Plasmid (h2) - sc-406151-NIC-2 from Santa Cruz Biotechnology
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RGMb CRISPR Activation Plasmid (h) - sc-406151-ACT from Santa Cruz Biotechnology
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RGMb CRISPR Activation Plasmid (h2) - sc-406151-ACT-2 from Santa Cruz Biotechnology
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RGMb Lentiviral Activation Particles (h) - sc-406151-LAC from Santa Cruz Biotechnology
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RGMb Lentiviral Activation Particles (h2) - sc-406151-LAC-2 from Santa Cruz Biotechnology
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RGMb siRNA (h) - sc-45736 from Santa Cruz Biotechnology
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RGMb shRNA Plasmid (h) - sc-45736-SH from Santa Cruz Biotechnology
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RGMb shRNA (h) Lentiviral Particles - sc-45736-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU155641 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18204 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18204 from Sigma-Aldrich
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RGMB siRNA (Human) - CRJ7126 from Cohesion Biosciences
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RGMB - MBS8231659 from MyBioSource
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shRNA set against Human RGMB (NM_001012761.2) - SHH394728 from Creative biogene
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Human RGMB siRNA - orb277627 from Biorbyt
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RGMB shRNA Plasmid (Human) - CHJ7126 from Cohesion Biosciences
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