| Gene Symbol |
KRT16
|
| Entrez Gene |
3868
|
| Alt Symbol |
CK16, FNEPPK, K16, K1CP, KRT16A, NEPPK, PC1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
keratin 16, type I
|
| Other Description |
CK-16|cytokeratin 16|cytokeratin-16|focal non-epidermolytic palmoplantar keratoderma|keratin, type I cytoskeletal 16|keratin-16
|
| Swissprots |
A8K488 P08779 Q9UBG8 Q16402 P30654
|
| Accessions |
AAA59460 AAB34564 AAD15829 EAW60749 P08779 AF061812 AAC99326 AK290853 BAF83542 AK309278 AK309296 BC039169 AAH39169 BM786499 DC394235 DQ891307 ABM82233 DQ896818 ABM87817 S72493 AAB30058 S79867 AAB35421 NM_005557 NP_005548
|
| Function |
Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance. {ECO:0000250|UniProtKB:Q9Z2K1}.
|
| Tissue Specificity |
Expressed in the hair follicle, nail bed and in mucosal stratified squamous epithelia and, suprabasally, in oral epithelium and palmoplantar epidermis. Also found in luminal cells of sweat and mammary gland ducts.
|
![Western Blot: Cytokeratin 16 Overexpression Lysate (Adult Normal) [NBL1-12383] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Cytokeratin 16.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/9093_Cytokeratin%252016%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-12383-img0002.jpg)