Gene Symbol | KRT16 |
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Entrez Gene | 3868 |
Alt Symbol | CK16, FNEPPK, K16, K1CP, KRT16A, NEPPK, PC1 |
Species | Human |
Gene Type | protein-coding |
Description | keratin 16, type I |
Other Description | CK-16|cytokeratin 16|cytokeratin-16|focal non-epidermolytic palmoplantar keratoderma|keratin, type I cytoskeletal 16|keratin-16 |
Swissprots | A8K488 P08779 Q9UBG8 Q16402 P30654 |
Accessions | AAA59460 AAB34564 AAD15829 EAW60749 P08779 AF061812 AAC99326 AK290853 BAF83542 AK309278 AK309296 BC039169 AAH39169 BM786499 DC394235 DQ891307 ABM82233 DQ896818 ABM87817 S72493 AAB30058 S79867 AAB35421 NM_005557 NP_005548 |
Function | Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance. {ECO:0000250|UniProtKB:Q9Z2K1}. |
Tissue Specificity | Expressed in the hair follicle, nail bed and in mucosal stratified squamous epithelia and, suprabasally, in oral epithelium and palmoplantar epidermis. Also found in luminal cells of sweat and mammary gland ducts. |
Cytokeratin 16 CRISPR/Cas9 KO Plasmid (h) - sc-403138 from Santa Cruz Biotechnology
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Cytokeratin 16 HDR Plasmid (h) - sc-403138-HDR from Santa Cruz Biotechnology
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Cytokeratin 16 Double Nickase Plasmid (h) - sc-403138-NIC from Santa Cruz Biotechnology
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Cytokeratin 16 Double Nickase Plasmid (h2) - sc-403138-NIC-2 from Santa Cruz Biotechnology
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Cytokeratin 16 CRISPR Activation Plasmid (h) - sc-403138-ACT from Santa Cruz Biotechnology
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Cytokeratin 16 CRISPR Activation Plasmid (h2) - sc-403138-ACT-2 from Santa Cruz Biotechnology
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Cytokeratin 16 Lentiviral Activation Particles (h) - sc-403138-LAC from Santa Cruz Biotechnology
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Cytokeratin 16 Lentiviral Activation Particles (h2) - sc-403138-LAC-2 from Santa Cruz Biotechnology
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Cytokeratin 16 siRNA (h) - sc-60498 from Santa Cruz Biotechnology
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Cytokeratin 16 shRNA Plasmid (h) - sc-60498-SH from Santa Cruz Biotechnology
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Cytokeratin 16 shRNA (h) Lentiviral Particles - sc-60498-V from Santa Cruz Biotechnology
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Cytokeratin 16 RNAi - H00003868-R01 from Novus Biologicals
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MISSION® esiRNA - EHU109781 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11361 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11361 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01344 from Sigma-Aldrich
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KRT16 siRNA (Human) - CRH2623 from Cohesion Biosciences
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shRNA set against Human KRT16 (NM_005557.3) - SHH327263 from Creative biogene
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shRNA set against Human KRT16(NM_005557.3) - SHL205410 from Creative biogene
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Human KRT16 siRNA - orb263125 from Biorbyt
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KRT16 shRNA Plasmid (Human) - CHH2623 from Cohesion Biosciences
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KRT16 miRNA 3'UTR clone - MiUTR1H-05442 from Creative biogene
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