Gene Symbol | CDC42EP2 |
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Entrez Gene | 10435 |
Alt Symbol | BORG1, CEP2 |
Species | Human |
Gene Type | protein-coding |
Description | CDC42 effector protein (Rho GTPase binding) 2 |
Other Description | CRIB-containing BOGR1 protein|binder of Rho GTPases 1|cdc42 effector protein 2 |
Swissprots | Q9UNS0 B2RD85 O14613 |
Accessions | AAN39381 EAW74374 O14613 AF001436 AAB81206 AF098290 AAD16185 AF163840 AAD48784 AK098292 BAG53607 AK315444 BAG37832 BC022337 AAH22337 BC075834 AAH75834 BT020004 AAV38807 DA251345 DQ891988 ABM82914 DQ895178 ABM86104 NM_006779 NP_006770 |
Function | Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner. {ECO:0000269|PubMed:10490598, ECO:0000269|PubMed:11035016}. |
Subcellular Location | Endomembrane system {ECO:0000269|PubMed:11035016}; Peripheral membrane protein {ECO:0000269|PubMed:11035016}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:11035016}. |
Tissue Specificity | Highly expressed in the heart. Weakly expressed in the pancreas and liver. {ECO:0000269|PubMed:10490598}. |
Cdc42EP2 (K-12) - sc-167442 from Santa Cruz Biotechnology
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Cdc42EP2 (T-14) - sc-167444 from Santa Cruz Biotechnology
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Anti-CDC42EP2 antibody - ab92673 from Abcam
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Anti-CDC42EP2 antibody - ab187312 from Abcam
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Anti-CDC42EP2 antibody - ab56716 from Abcam
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Anti-CDC42EP2 antibody - ab172387 from Abcam
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Anti-CDC42EP2 antibody - C-terminal - ab173012 from Abcam
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Anti-CDC42EP2 Antibody (aa132-160, AP) - LS-C254278 from LifeSpan Bioscience
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Anti-CDC42EP2 Antibody (aa132-160, APC) - LS-C254279 from LifeSpan Bioscience
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Anti-CDC42EP2 Antibody (aa132-160, Biotin) - LS-C254280 from LifeSpan Bioscience
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Anti-CDC42EP2 Antibody (aa132-160, FITC) - LS-C254281 from LifeSpan Bioscience
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Anti-CDC42EP2 Antibody (aa132-160, Azide-free, HRP) - LS-C254282 from LifeSpan Bioscience
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Anti-CDC42EP2 Antibody (aa102-210) - LS-C306865 from LifeSpan Bioscience
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Anti-CDC42EP2 Antibody (aa132-160, PE) - LS-C254283 from LifeSpan Bioscience
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Anti-CDC42EP2 Antibody (aa132-160) - LS-C320234 from LifeSpan Bioscience
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Anti-CDC42EP2 Antibody - LS-C155515 from LifeSpan Bioscience
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Anti-CDC42EP2 Antibody (Leu24) - LS-C177807 from LifeSpan Bioscience
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Anti-CDC42EP2 Antibody (aa10-59) IHC-plus™ - LS-B9713 from LifeSpan Bioscience
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Anti-CDC42EP2 Antibody (aa132-160) - LS-C168592 from LifeSpan Bioscience
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CDC42EP2 Antibody - NBP1-88383 from Novus Biologicals
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CDC42EP2 Antibody - NBP1-51340 from Novus Biologicals
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CDC42EP2 Antibody - NBP2-15833 from Novus Biologicals
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CDC42EP2 Antibody (2H7) - H00010435-M01 from Novus Biologicals
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CDC42EP2 Antibody - H00010435-A01 from Novus Biologicals
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CDC42EP2 Antibody - H00010435-D01P from Novus Biologicals
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