Gene Symbol | HIST1H2AA |
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Entrez Gene | 221613 |
Alt Symbol | H2AA, H2AFR, bA317E16.2 |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 1, H2aa |
Other Description | H2A histone family, member R|histone 1, H2aa|histone H2A type 1-A|histone H2A/r |
Swissprots | Q96QV6 |
Accessions | AAN59963 EAW55489 Q96QV6 BC062211 AAH62211 HQ447550 ADQ32036 NM_170745 NP_734466 |
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Subcellular Location | Nucleus. Chromosome. |
Top Pathways | Systemic lupus erythematosus, Alcoholism |
HIST1H2AA-Over-expression-Lysate - LY16006a from Abgent, a WuXi AppTec company
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HIST1H2AA overexpression lysate - LY406865 from Acris Antibodies
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HIST1H2AA 293 Cell Lysate - 404051 from ABBIOTEC
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HIST1H2AA Overexpression Lysate (Native) - NBL1-11556 from Novus Biologicals
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HIST1H2AA Over-expression Lysate Product - GWB-C8E38F from Genway Biotech
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Panoply™ Human HIST1H2AA Knockdown Stable Cell Line - CSC-DC007013 from Creative biogene
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