Gene Symbol | HIST1H2AA |
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Entrez Gene | 221613 |
Alt Symbol | H2AA, H2AFR, bA317E16.2 |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 1, H2aa |
Other Description | H2A histone family, member R|histone 1, H2aa|histone H2A type 1-A|histone H2A/r |
Swissprots | Q96QV6 |
Accessions | AAN59963 EAW55489 Q96QV6 BC062211 AAH62211 HQ447550 ADQ32036 NM_170745 NP_734466 |
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Subcellular Location | Nucleus. Chromosome. |
Top Pathways | Systemic lupus erythematosus, Alcoholism |
Histone cluster 1 H2AA CRISPR/Cas9 KO Plasmid (h) - sc-415137 from Santa Cruz Biotechnology
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Histone cluster 1 H2AA HDR Plasmid (h) - sc-415137-HDR from Santa Cruz Biotechnology
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Histone cluster 1 H2AA Double Nickase Plasmid (h) - sc-415137-NIC from Santa Cruz Biotechnology
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Histone cluster 1 H2AA Double Nickase Plasmid (h2) - sc-415137-NIC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2AA CRISPR Activation Plasmid (h) - sc-415137-ACT from Santa Cruz Biotechnology
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Histone cluster 1 H2AA CRISPR Activation Plasmid (h2) - sc-415137-ACT-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2AA Lentiviral Activation Particles (h) - sc-415137-LAC from Santa Cruz Biotechnology
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Histone cluster 1 H2AA Lentiviral Activation Particles (h2) - sc-415137-LAC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2AA siRNA (h) - sc-105459 from Santa Cruz Biotechnology
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Histone cluster 1 H2AA shRNA Plasmid (h) - sc-105459-SH from Santa Cruz Biotechnology
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Histone cluster 1 H2AA shRNA (h) Lentiviral Particles - sc-105459-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN10056 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10056 from Sigma-Aldrich
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HIST1H2AA siRNA (Human) - CRJ6528 from Cohesion Biosciences
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HIST1H2AA RNAi - H00221613-R01 from Novus Biologicals
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HIST1H2AA - MBS8206141 from MyBioSource
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shRNA set against Human HIST1H2AA (NM_170745.3) - SHH312421 from Creative biogene
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shRNA set against Human HIST1H2AA(NM_170745.3) - SHH121781 from Creative biogene
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HIST1H2AA shRNA Plasmid (Human) - CHJ6528 from Cohesion Biosciences
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HIST1H2AA miRNA 3'UTR clone - MiUTR1H-04519 from Creative biogene
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