DAGLA

Gene Symbol DAGLA
Entrez Gene 747
Alt Symbol C11orf11, DAGL(ALPHA), DAGLALPHA, NSDDR
Species Human
Gene Type protein-coding
Description diacylglycerol lipase, alpha
Other Description DGL-alpha|neural stem cell-derived dendrite regulator|sn1-specific diacylglycerol lipase alpha
Swissprots Q6WQJ0 Q9Y4D2 A7E233
Accessions EAW73959 EAW73960 EAW73961 EAW73962 Q9Y4D2 AB014559 BAA31634 AI702626 AY275377 AAQ17119 BC150176 AAI50177 BC150195 AAI50196 BC152453 AAI52454 BI963857 XM_005274230 XP_005274287 XM_011545235 XP_011543537 XM_011545236 XP_011543538 NM_006133 NP_006124
Function Catalyzes the hydrolysis of diacylglycerol (DAG) to 2- arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling at mature synapses. {ECO:0000269|PubMed:14610053}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Highly expressed in brain and pancreas. {ECO:0000269|PubMed:14610053, ECO:0000269|PubMed:16051747}.
Top Pathways Retrograde endocannabinoid signaling

DAGLα CRISPR/Cas9 KO Plasmid (h) - sc-402826 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAGLα HDR Plasmid (h) - sc-402826-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAGLα Double Nickase Plasmid (h) - sc-402826-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAGLα Double Nickase Plasmid (h2) - sc-402826-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAGLα CRISPR Activation Plasmid (h) - sc-402826-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAGLα CRISPR Activation Plasmid (h2) - sc-402826-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAGLα Lentiviral Activation Particles (h) - sc-402826-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAGLα Lentiviral Activation Particles (h2) - sc-402826-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAGLα siRNA (h) - sc-96964 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DAGLα shRNA Plasmid (h) - sc-96964-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DAGLα shRNA (h) Lentiviral Particles - sc-96964-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU139041 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6919 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6919 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

DAGLA siRNA (Human) - CRH0519 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DAGLA - MBS8229529 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DAGLα CRISPR/Cas9 KO Plasmid (h2) - sc-402826-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAGLα HDR Plasmid (h2) - sc-402826-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human DAGLA (NM_006133.2) - SHH274437 from Creative biogene

Category siRNA
Species Reactivities Human

DAGLA shRNA Plasmid (Human) - CHH0519 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DAGLA miRNA 3'UTR clone - MiUTR4H-TG02553 from Creative biogene

Species Reactivities Human
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