| Gene Symbol |
L3HYPDH
|
| Entrez Gene |
112849
|
| Alt Symbol |
C14orf149
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
L-3-hydroxyproline dehydratase (trans-)
|
| Other Description |
probable proline racemase|trans-3-hydroxy-L-proline dehydratase|trans-3-hydroxy-l-proline dehydratase|trans-3-hydroxyl-L-proline dehydratase|trans-L-3-hydroxyproline dehydratase
|
| Swissprots |
Q96LJ5 Q96EM0
|
| Accessions |
EAW80752 Q96EM0 AK058165 BAB71696 AK294843 BAG57949 BC012131 AAH12131 XM_005267298 XP_005267355 XM_011536386 XP_011534688 XM_011536387 XP_011534689 XM_011536388 XP_011534690 XR_245661 XR_943382 XR_943383 XR_943384 XR_943385 XR_943386 NM_144581 NP_653182
|
| Function |
Catalyzes the dehydration of trans-3-hydroxy-L-proline to Delta(1)-pyrroline-2-carboxylate (Pyr2C). May be required to degrade trans-3-hydroxy-L-proline from the diet and originating from the degradation of proteins such as collagen-IV that contain it. {ECO:0000269|PubMed:22528483}.
|
| Tissue Specificity |
Ubiquitously expressed. {ECO:0000269|PubMed:22528483}.
|
| Top Pathways |
Arginine and proline metabolism
|