| Gene Symbol |
Ccndbp1
|
| Entrez Gene |
17151
|
| Alt Symbol |
AU022347, DIP1, GCIP, Maid, SECC-8, SSEC-8
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
cyclin D-type binding-protein 1
|
| Other Description |
cyclin-D1-binding protein 1|grap2 and cyclin-D-interacting protein|maternal Id-like protein|maternal inhibition of differentiation|stage specific embryonic cDNA-8 protein
|
| Swissprots |
Q61162 Q3TVC7 Q99JA7 Q3UMI3 Q99KG4
|
| Accessions |
EDL28027 EDL28028 EDL28029 Q3TVC7 AK144883 BAE26115 AK154285 BAE32489 AK160205 BAE35692 AK163150 BAE37214 AK167345 BAE39444 AK186314 AK198998 AK211891 BB517577 BC001984 AAH01984 BC004673 AAH04673 BC005802 AAH05802 CO810054 U50734 AAB58118 XM_006498851 XP_006498914 XM_006498852 XP_006498915 XM_011239329 XP_011237631 NM_010761 NP_034891
|
| Function |
May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F- dependent transcription (By similarity). May be required for hepatocyte proliferation. {ECO:0000250, ECO:0000269|PubMed:17256742}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
|
| Tissue Specificity |
Expressed at high levels in brain, intestine, muscle and ovary and at lower levels in heart, kidney, liver, lung, spleen and testis. {ECO:0000269|PubMed:9186056}.
|
