Gene Symbol | Ccndbp1 |
---|---|
Entrez Gene | 17151 |
Alt Symbol | AU022347, DIP1, GCIP, Maid, SECC-8, SSEC-8 |
Species | Mouse |
Gene Type | protein-coding |
Description | cyclin D-type binding-protein 1 |
Other Description | cyclin-D1-binding protein 1|grap2 and cyclin-D-interacting protein|maternal Id-like protein|maternal inhibition of differentiation|stage specific embryonic cDNA-8 protein |
Swissprots | Q61162 Q3TVC7 Q99JA7 Q3UMI3 Q99KG4 |
Accessions | EDL28027 EDL28028 EDL28029 Q3TVC7 AK144883 BAE26115 AK154285 BAE32489 AK160205 BAE35692 AK163150 BAE37214 AK167345 BAE39444 AK186314 AK198998 AK211891 BB517577 BC001984 AAH01984 BC004673 AAH04673 BC005802 AAH05802 CO810054 U50734 AAB58118 XM_006498851 XP_006498914 XM_006498852 XP_006498915 XM_011239329 XP_011237631 NM_010761 NP_034891 |
Function | May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F- dependent transcription (By similarity). May be required for hepatocyte proliferation. {ECO:0000250, ECO:0000269|PubMed:17256742}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Tissue Specificity | Expressed at high levels in brain, intestine, muscle and ovary and at lower levels in heart, kidney, liver, lung, spleen and testis. {ECO:0000269|PubMed:9186056}. |
GCIP CRISPR/Cas9 KO Plasmid (m) - sc-421548 from Santa Cruz Biotechnology
|
||||||||
GCIP HDR Plasmid (m) - sc-421548-HDR from Santa Cruz Biotechnology
|
||||||||
GCIP Double Nickase Plasmid (m) - sc-421548-NIC from Santa Cruz Biotechnology
|
||||||||
GCIP Double Nickase Plasmid (m2) - sc-421548-NIC-2 from Santa Cruz Biotechnology
|
||||||||
GCIP CRISPR Activation Plasmid (m) - sc-421548-ACT from Santa Cruz Biotechnology
|
||||||||
GCIP CRISPR Activation Plasmid (m2) - sc-421548-ACT-2 from Santa Cruz Biotechnology
|
||||||||
GCIP Lentiviral Activation Particles (m) - sc-421548-LAC from Santa Cruz Biotechnology
|
||||||||
GCIP Lentiviral Activation Particles (m2) - sc-421548-LAC-2 from Santa Cruz Biotechnology
|
||||||||
GCIP siRNA (m) - sc-145361 from Santa Cruz Biotechnology
|
||||||||
GCIP shRNA Plasmid (m) - sc-145361-SH from Santa Cruz Biotechnology
|
||||||||
GCIP shRNA (m) Lentiviral Particles - sc-145361-V from Santa Cruz Biotechnology
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN28259 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND28259 from Sigma-Aldrich
|
||||||||
CCNDBP1 siRNA (Mouse) - CRM2446 from Cohesion Biosciences
|
||||||||
CCNDBP1 - MBS8237812 from MyBioSource
|
||||||||
shRNA set against Mouse CCNDBP1 (NM_010761.2) - SHH257873 from Creative biogene
|
||||||||
shRNA set against Mouse Ccndbp1(NM_010761.2) - SHG152263 from Creative biogene
|
||||||||
CCNDBP1 shRNA Plasmid (Mouse) - CHM2446 from Cohesion Biosciences
|
||||||||
CCNDBP1 miRNA 3'UTR clone - MiUTR1M-02690 from Creative biogene
|