Gene Symbol | Mccc2 |
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Entrez Gene | 361884 |
Alt Symbol | - |
Species | Rat |
Gene Type | protein-coding |
Description | methylcrotonoyl-CoA carboxylase 2 (beta) |
Other Description | 3-methylcrotonyl-CoA carboxylase 2|3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit|3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta|MCCase subunit beta|methylcrotonoyl-CoA carboxylase beta chain, mitochondrial|methylcrotonoyl-Coenzyme A carboxylase 2 (beta) |
Swissprots | Q5XIT9 |
Accessions | Q5XIT9 BC083581 AAH83581 XM_008760678 XP_008758900 NM_001012177 NP_001012177 |
Function | Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism. {ECO:0000250}. |
Subcellular Location | Mitochondrion matrix {ECO:0000250}. |
Top Pathways | Valine, leucine and isoleucine degradation |
CompoZr® Knockout ZFN Kit - CKOZFN57070 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND57070 from Sigma-Aldrich
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MCCC2 siRNA (Rat) - CRR5940 from Cohesion Biosciences
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shRNA set against Rat MCCC2 (NM_001012177.1) - SHH339175 from Creative biogene
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shRNA set against Rat Mccc2(NM_001012177.1) - SHH180797 from Creative biogene
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Rat MCCC2 siRNA - orb300789 from Biorbyt
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MCCC2 shRNA Plasmid (Rat) - CHR5940 from Cohesion Biosciences
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MCCC2 miRNA 3'UTR clone - MiUTR1R-03728 from Creative biogene
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