Gene Symbol | LY86 |
---|---|
Entrez Gene | 9450 |
Alt Symbol | MD-1, MD1, MMD-1, dJ80N2.1 |
Species | Human |
Gene Type | protein-coding |
Description | lymphocyte antigen 86 |
Other Description | MD-1, RP105-associated|ly-86|protein MD-1 |
Swissprots | O95711 Q9UQC4 |
Accessions | EAW55191 EAW55192 O95711 AB020499 BAA76410 AF057178 AAC98152 AY931019 AAY17402 BC038846 AAH38846 CD695164 HQ448028 ADQ32509 NM_004271 NP_004262 |
Function | May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted, extracellular space. Note=Associated with CD180 at the cell surface. |
Tissue Specificity | Highly expressed in B-cells, monocytes and tonsil. |