Gene Symbol | LY86 |
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Entrez Gene | 9450 |
Alt Symbol | MD-1, MD1, MMD-1, dJ80N2.1 |
Species | Human |
Gene Type | protein-coding |
Description | lymphocyte antigen 86 |
Other Description | MD-1, RP105-associated|ly-86|protein MD-1 |
Swissprots | O95711 Q9UQC4 |
Accessions | EAW55191 EAW55192 O95711 AB020499 BAA76410 AF057178 AAC98152 AY931019 AAY17402 BC038846 AAH38846 CD695164 HQ448028 ADQ32509 NM_004271 NP_004262 |
Function | May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted, extracellular space. Note=Associated with CD180 at the cell surface. |
Tissue Specificity | Highly expressed in B-cells, monocytes and tonsil. |
MD-1 CRISPR/Cas9 KO Plasmid (h) - sc-411282 from Santa Cruz Biotechnology
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MD-1 HDR Plasmid (h) - sc-411282-HDR from Santa Cruz Biotechnology
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MD-1 Double Nickase Plasmid (h) - sc-411282-NIC from Santa Cruz Biotechnology
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MD-1 Double Nickase Plasmid (h2) - sc-411282-NIC-2 from Santa Cruz Biotechnology
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MD-1 CRISPR Activation Plasmid (h) - sc-411282-ACT from Santa Cruz Biotechnology
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MD-1 CRISPR Activation Plasmid (h2) - sc-411282-ACT-2 from Santa Cruz Biotechnology
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MD-1 Lentiviral Activation Particles (h) - sc-411282-LAC from Santa Cruz Biotechnology
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MD-1 Lentiviral Activation Particles (h2) - sc-411282-LAC-2 from Santa Cruz Biotechnology
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MD-1 siRNA (h) - sc-40734 from Santa Cruz Biotechnology
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MD-1 shRNA Plasmid (h) - sc-40734-SH from Santa Cruz Biotechnology
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MD-1 shRNA (h) Lentiviral Particles - sc-40734-V from Santa Cruz Biotechnology
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MD-1/LY86 RNAi - H00009450-R01 from Novus Biologicals
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MISSION® esiRNA - EHU042441 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12844 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12844 from Sigma-Aldrich
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LY86 siRNA (Human) - CRH6268 from Cohesion Biosciences
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shRNA set against Human LY86 (NM_004271.3) - SHH335907 from Creative biogene
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Human LY86 siRNA - orb266770 from Biorbyt
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LY86 shRNA Plasmid (Human) - CHH6268 from Cohesion Biosciences
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LY86 miRNA 3'UTR clone - MiUTR1H-05963 from Creative biogene
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