| Gene Symbol |
IQCB1
|
| Entrez Gene |
9657
|
| Alt Symbol |
NPHP5, PIQ, SLSN5
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
IQ motif containing B1
|
| Other Description |
IQ calmodulin-binding motif containing 1|IQ calmodulin-binding motif-containing protein 1|nephrocystin 5|p53 and DNA damage-regulated IQ motif protein
|
| Swissprots |
Q8NI79 Q5DKQ7 Q9BS08 Q3KS09 Q3KS08 Q15051
|
| Accessions |
EAW79499 EAW79500 EAW79501 Q15051 AB062481 BAB93506 AL042102 AY714228 AAW47233 AY964667 AAY46029 AY964668 AAY46030 BC005806 AAH05806 BG721354 BM682018 BQ068103 BX393165 D25278 BAA04968 XM_005247911 XP_005247968 XM_005247912 XP_005247969 XM_005247913 XP_005247970 XM_011513335 XP_011511637 XR_924221 NM_001023570 NP_001018864 NM_001023571 NP_001018865
|
| Function |
Involved in ciliogenesis. {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:21565611}. Note=Localization to the centrosome depends on the interaction with CEP290.
|
| Tissue Specificity |
Ubiquitously expressed in fetal and adult tissues. Localized to the outer segments and connecting cilia of photoreceptor cells. Up-regulated in a number of primary colorectal and gastric tumors. {ECO:0000269|PubMed:15723066, ECO:0000269|PubMed:16322217}.
|