STT3B

Gene Symbol STT3B
Entrez Gene 201595
Alt Symbol CDG1X, SIMP, STT3-B
Species Human
Gene Type protein-coding
Description STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
Other Description STT3, subunit of the oligosaccharyltransferase complex, homolog B|dolichyl-diphosphooligosaccharide protein glycotransferase|dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B|homolog of yeast STT3|oligosaccharyl transferase subunit STT3B|source of immunodominant MHC-associated peptides homolog
Swissprots Q96JZ4 Q96KY7 Q8TCJ2
Accessions CAF85831 EAW64415 EAW64416 Q8TCJ2 AI914841 AK027789 BAB55370 AK074587 AK075380 BAC11581 AK311488 AX799082 CAE48447 AY074880 AAL71884 BC015880 AAH15880 HY015137 HY039873 XM_011533465 XP_011531767 NM_178862 NP_849193
Function Catalytic subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). STT3B is present in a small subset of OST complexes and mediates both cotranslational and post-translational N-glycosylation of target proteins: STT3B-containing complexes are required for efficient cotranslational glycosylation and while they are less competent than STT3A-containing complexes for cotranslational glycosylation, they have the ability to mediate glycosylation of some nascent sites that are not accessible for STT3A. STT3B-containing complexes also act post-translationally and mediate modification of skip
Subcellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity Expressed in heart, brain, placenta, lung, liver, muscle, kidney and pancreas. Expressed in skin fibroblasts (at protein level). {ECO:0000269|PubMed:12887896}.
Top Pathways N-Glycan biosynthesis, Protein processing in endoplasmic reticulum

SIMP (K-14) - sc-100148 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
SIMP (K-14): sc-100148. Western blot analysis of SIMP expression in HL-60 (A) and CCRF-CEM (B) whole cell lysates.

SIMP (N-15) - sc-100149 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-STT3B antibody - ab122351 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab122351, at 1/600 dilution, staining STT3B in paraffin-embedded Human testis tissue by Immunohistochemistry.

STT3B Antibody - NBP1-81884 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-STT3B antibody produced in rabbit - HPA036646 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-STT3B: <B>Cat. No. HPA036646</B>: Immunohistochemical staining of human testis shows strong cytoplasmic positivity in spermatogonia.

STT3B antibody - 70R-20617 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Stt3b Antibody - abx115879 from Abbexa

Host Rabbit
Clonality Polyclonal

STT3B / SIMP antibody - 15323-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Human brain were subjected to SDS PAGE followed by western blot with 15323-1-AP(STT3B Antibody) at dilution of 1:2000

STT3B antibody - 15323-1-AP from Proteintech Group

Prices $279.00
Sizes con: 57 μg/150μl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of ( -20℃ Ethanol) fixed HepG2 cells using 15323-1-AP (STT3B antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Anti-STT3B (aa 492-533) polyclonal antibody - DPABH-20647 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Anti-STT3B monoclonal antibody - DCABH-201552 from Creative Diagnostics

Host Rabbit
Clonality Monoclonal

STT3, subunit of the oligosaccharyltransferase complex, homolog B, Polyclonal Antibody - MBS711510 from MyBioSource

Prices $230.00, $500.00
Sizes 50 µl, 150 µl
Host Rabbit
Clonality Polyclonal

STT3B Antibody - CSB-PA022886GA01HU from Cusabio

Host Rabbit

Polyclonal Antibody to Fibroblast Activation Protein Alpha (FAPa) - PAC469Hu01 from Cloud-clone

Host Rabbit
Clonality Polyclonal

STT3B - A9091 from NeoScientific

Prices $480.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

STT3B Polyclonal Antibody - A9091 from ABclonal

Prices $200.00, $480.00
Sizes 50 µl, 200 µl
Host Rabbit
Clonality Polyclonal

STT3B Antibody - abx124903 from Abbexa

Host Rabbit
Clonality Polyclonal

STT3B Antibody - abx145706 from Abbexa

Host Rabbit
Clonality Polyclonal

STT3B Antibody - NBP2-48657 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: STT3B Antibody [NBP2-48657] - Staining of human testis shows cytoplasmic positivity in seminiferus ducts and leydig cells.

Anti-STT3B antibody produced in rabbit - HPA036448 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-STT3B: <B>Cat. No. HPA036448</B>: Immunohistochemical staining of human testis shows cytoplasmic positivity in seminiferus ducts and leydig cells.

anti-STT3B antibody - A008356 from Biobool

Host Rabbit
Clonality Polyclonal

STT3B antibody - C-terminal region (OAAB02299) - OAAB02299 from Aviva Systems Biology

Host Rabbit
Clonality Polyclonal

STT3B, Polyclonal Antibody - MBS7604589 from MyBioSource

Prices $290.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

STT3B antibody - DF12327 from Affinity Biosciences

Prices $280.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of mouse liver tissue, using STT3B antibody.
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