Gene Symbol |
TRIO
|
Entrez Gene |
7204
|
Alt Symbol |
ARHGEF23, tgat
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
trio Rho guanine nucleotide exchange factor
|
Other Description |
PTPRF-interacting protein|triple functional domain (PTPRF interacting)|triple functional domain protein
|
Swissprots |
Q6PJC9 Q59EQ7 Q13458 Q8IWK8 O75962 Q6ZN05 D3DTD1
|
Accessions |
EAX08044 EAX08045 EAX08046 EAX08047 EAX08048 O75962 AB115332 BAC79392 AB209754 BAD92991 AF091395 AAC43042 AI478154 AK124770 AK131423 BAD18570 AK304786 BAG65537 AL161955 BC017268 AAH17268 BC035585 AAH35585 BF058117 BQ009698 BQ691537 U42390 AAC34245 XM_011514107 XP_011512409 XM_011514108 XP_011512410 XM_011514109 XP_011512411 XM_011514110 XP_011512412 XM_011514111 XP_011512413 XM_011514112 XP_011512414 XM_011514113 XP_011512415 XR_241714 NM_007118 NP_009049
|
Function |
Promotes the exchange of GDP by GTP. Together with leukocyte antigen-related (LAR) protein, it could play a role in coordinating cell-matrix and cytoskeletal rearrangements necessary for cell migration and cell growth.
|
Subcellular Location |
Cytoplasm {ECO:0000250}.
|
Tissue Specificity |
Highly expressed in heart, skeletal muscle, brain, pancreas, placenta, liver, kidney and lung.
|