Gene Symbol | TRIO |
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Entrez Gene | 7204 |
Alt Symbol | ARHGEF23, tgat |
Species | Human |
Gene Type | protein-coding |
Description | trio Rho guanine nucleotide exchange factor |
Other Description | PTPRF-interacting protein|triple functional domain (PTPRF interacting)|triple functional domain protein |
Swissprots | Q6PJC9 Q59EQ7 Q13458 Q8IWK8 O75962 Q6ZN05 D3DTD1 |
Accessions | EAX08044 EAX08045 EAX08046 EAX08047 EAX08048 O75962 AB115332 BAC79392 AB209754 BAD92991 AF091395 AAC43042 AI478154 AK124770 AK131423 BAD18570 AK304786 BAG65537 AL161955 BC017268 AAH17268 BC035585 AAH35585 BF058117 BQ009698 BQ691537 U42390 AAC34245 XM_011514107 XP_011512409 XM_011514108 XP_011512410 XM_011514109 XP_011512411 XM_011514110 XP_011512412 XM_011514111 XP_011512413 XM_011514112 XP_011512414 XM_011514113 XP_011512415 XR_241714 NM_007118 NP_009049 |
Function | Promotes the exchange of GDP by GTP. Together with leukocyte antigen-related (LAR) protein, it could play a role in coordinating cell-matrix and cytoskeletal rearrangements necessary for cell migration and cell growth. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Tissue Specificity | Highly expressed in heart, skeletal muscle, brain, pancreas, placenta, liver, kidney and lung. |
Trio CRISPR/Cas9 KO Plasmid (h) - sc-401231 from Santa Cruz Biotechnology
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Trio HDR Plasmid (h) - sc-401231-HDR from Santa Cruz Biotechnology
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Trio Double Nickase Plasmid (h) - sc-401231-NIC from Santa Cruz Biotechnology
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Trio Double Nickase Plasmid (h2) - sc-401231-NIC-2 from Santa Cruz Biotechnology
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Trio CRISPR Activation Plasmid (h) - sc-401231-ACT from Santa Cruz Biotechnology
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Trio CRISPR Activation Plasmid (h2) - sc-401231-ACT-2 from Santa Cruz Biotechnology
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Trio Lentiviral Activation Particles (h) - sc-401231-LAC from Santa Cruz Biotechnology
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Trio Lentiviral Activation Particles (h2) - sc-401231-LAC-2 from Santa Cruz Biotechnology
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Trio siRNA (h) - sc-36724 from Santa Cruz Biotechnology
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Trio shRNA Plasmid (h) - sc-36724-SH from Santa Cruz Biotechnology
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Trio shRNA (h) Lentiviral Particles - sc-36724-V from Santa Cruz Biotechnology
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TRIO RNAi - H00007204-R02 from Novus Biologicals
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MISSION® esiRNA - EHU083121 from Sigma-Aldrich
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MISSION® siRNA - SIHK2347 from Sigma-Aldrich
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MISSION® siRNA - SIHK2345 from Sigma-Aldrich
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MISSION® siRNA - SIHK2346 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22025 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22025 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07309 from Sigma-Aldrich
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TRIO siRNA (Human) - CRH4942 from Cohesion Biosciences
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TRIO - MBS8216910 from MyBioSource
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Trio CRISPR/Cas9 KO Plasmid (h2) - sc-401231-KO-2 from Santa Cruz Biotechnology
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Trio HDR Plasmid (h2) - sc-401231-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human TRIO(NM_007118.2) - SHL095580 from Creative biogene
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Human TRIO siRNA - orb265444 from Biorbyt
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