| Gene Symbol |
UPK2
|
| Entrez Gene |
7379
|
| Alt Symbol |
UP2, UPII
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
uroplakin 2
|
| Other Description |
uroplakin II|uroplakin-2
|
| Swissprots |
O00457 Q53YV0 B0YJ92 O00526
|
| Accessions |
ACA06070 BAB84089 O00526 AB009454 BAA23884 AF000562 AAB58416 AY455312 AAR19396 BC113900 AAI13901 CD556028 Y13645 CAA73996 NM_006760 NP_006751
|
| Function |
Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in regulating the assembly of the AUM (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Note=Heterodimer formation with UPK1A is a prerequisite to exit out of the endoplasmic reticulum (ER). {ECO:0000250}.
|
| Tissue Specificity |
Expressed in ureter. {ECO:0000269|PubMed:9846985}.
|
![Western Blot: Uroplakin II Overexpression Lysate (Adult Normal) [NBP2-10399] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Uroplakin II.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2747_Uroplakin%2520II%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10399-img0001.jpg)