Gene Symbol | UPK2 |
---|---|
Entrez Gene | 7379 |
Alt Symbol | UP2, UPII |
Species | Human |
Gene Type | protein-coding |
Description | uroplakin 2 |
Other Description | uroplakin II|uroplakin-2 |
Swissprots | O00457 Q53YV0 B0YJ92 O00526 |
Accessions | ACA06070 BAB84089 O00526 AB009454 BAA23884 AF000562 AAB58416 AY455312 AAR19396 BC113900 AAI13901 CD556028 Y13645 CAA73996 NM_006760 NP_006751 |
Function | Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in regulating the assembly of the AUM (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Note=Heterodimer formation with UPK1A is a prerequisite to exit out of the endoplasmic reticulum (ER). {ECO:0000250}. |
Tissue Specificity | Expressed in ureter. {ECO:0000269|PubMed:9846985}. |
UPII CRISPR/Cas9 KO Plasmid (h) - sc-402242 from Santa Cruz Biotechnology
|
||||||||
UPII HDR Plasmid (h) - sc-402242-HDR from Santa Cruz Biotechnology
|
||||||||
UPII Double Nickase Plasmid (h) - sc-402242-NIC from Santa Cruz Biotechnology
|
||||||||
UPII Double Nickase Plasmid (h2) - sc-402242-NIC-2 from Santa Cruz Biotechnology
|
||||||||
UPII CRISPR Activation Plasmid (h) - sc-402242-ACT from Santa Cruz Biotechnology
|
||||||||
UPII CRISPR Activation Plasmid (h2) - sc-402242-ACT-2 from Santa Cruz Biotechnology
|
||||||||
UPII Lentiviral Activation Particles (h) - sc-402242-LAC from Santa Cruz Biotechnology
|
||||||||
UPII Lentiviral Activation Particles (h2) - sc-402242-LAC-2 from Santa Cruz Biotechnology
|
||||||||
UPII siRNA (h) - sc-41094 from Santa Cruz Biotechnology
|
||||||||
UPII shRNA Plasmid (h) - sc-41094-SH from Santa Cruz Biotechnology
|
||||||||
UPII shRNA (h) Lentiviral Particles - sc-41094-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU030641 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN22522 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22522 from Sigma-Aldrich
|
||||||||
UPK2 siRNA (Human) - CRH5048 from Cohesion Biosciences
|
||||||||
UPK2 - MBS8204801 from MyBioSource
|
||||||||
shRNA set against Human UPK2 (NM_006760.3) - SHH440800 from Creative biogene
|
||||||||
Human UPK2 siRNA - orb265550 from Biorbyt
|
||||||||
UPK2 shRNA Plasmid (Human) - CHH5048 from Cohesion Biosciences
|
||||||||
UPK2 miRNA 3'UTR clone - MiUTR4H-TG09677 from Creative biogene
|