Irx3

Gene Symbol Irx3
Entrez Gene 16373
Alt Symbol AI894186
Species Mouse
Gene Type protein-coding
Description Iroquois related homeobox 3
Other Description homeodomain protein IRXB1|iroquois homeobox protein 3|iroquois-class homeodomain protein IRX-3
Swissprots Q3UPZ3 Q5U3K8 P81067
Accessions EDL11081 P81067 AK143023 BAE25251 BC020464 BC067195 BC085500 AAH85500 Y15001 CAA75233 NM_001253822 NP_001240751 NM_008393 NP_032419
Function Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells. {ECO:0000269|PubMed:10830170, ECO:0000269|PubMed:15201216}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Expressed by neural progenitor cells in discrete domains of the ventral neural tube. Also expressed in specific and overlapping patterns with Irx1 and Irx2 in the developing and adult metanephric kidney. In the adult metanephros, renal expression is confined to the S3 segment of the proximal tubule, in the loop of Henle. {ECO:0000269|PubMed:10830170, ECO:0000269|PubMed:17875669}.

IRX3 (M-15) - sc-22581 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
IRX3 (M-15): sc-22581. Western blot analysis of IRX3 expression in Sol8 nuclear extract.

IRX3 Antibody - NBP1-80217 from Novus Biologicals

Prices $139.00, $299.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

Anti-IRX3 antibody produced in rabbit - AV36905 from Sigma-Aldrich

Prices $267.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: NIH/3T3 (<B>Cat. No. AV36905</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 5.0 μg/mL in cell type NIH/3T3

IRX3 antibody - N-terminal region (ARP36905_T100) - ARP36905_T100 from Aviva Systems Biology

Prices $229.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

IRX3 antibody - 70R-31797 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

IRX3 antibody - 20R-1124 from Fitzgerald

Prices $290.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

IRX3 Antibody - 28-585 from ProSci

Prices $250.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Antibody used in WB on Mouse NIH-3T3 at 5.0 ug/ml.

IRX3 Antibody - GWB-7B827E from Genway Biotech

Prices $294.00
Sizes 100 µg
Clonality Polyclonal

IRX3, Polyclonal Antibody - MBS834818 from MyBioSource

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

IRX3 / IRXB1 antibody - TA341786 from Acris Antibodies

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
WB Suggested Anti-IRX3 Antibody Titration: 5.0 ug/ml; ELISA Titer: 1:1562500; Positive Control: NIH/3T3 cell lysate

IRX3 antibody - N-terminal region : Biotin (ARP36905_T100-Biotin) - ARP36905_T100-Biotin from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

IRX3 antibody - N-terminal region : FITC (ARP36905_T100-FITC) - ARP36905_T100-FITC from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

IRX3 antibody - N-terminal region : HRP (ARP36905_T100-HRP) - ARP36905_T100-HRP from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Search more