| Gene Symbol |
CCDC176
|
| Entrez Gene |
80127
|
| Alt Symbol |
C14orf45
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
coiled-coil domain containing 176
|
| Other Description |
basal body-orientation factor 1|coiled-coil domain-containing protein 176
|
| Swissprots |
Q8ND07 Q0P604 Q9H5P8
|
| Accessions |
EAW81157 Q8ND07 AK026842 BAB15572 AK097531 BAG53483 AL834487 CAD39145 BC044808 BC104979 AAI04980 BC104981 AAI04982 DB484577 DB493409 XM_005268092 XP_005268149 XM_005268097 XP_005268154 XM_005268098 XP_005268155 XM_011537170 XP_011535472 XM_011537171 XP_011535473 XM_011537172 XP_011535474 XM_011537173 XP_011535475 XM_011537174 XP_011535476 XM_011537175 XP_011535477 XM_011537176 XP_011535478 XM_011537177 XP_011535479 XM_011537178 XP_011535480 XM_011537179 XP_011535481 XM_011537180 XP_011535482 XR_245725 NM_025057 NP_079333
|
| Function |
Basal body protein required in multiciliate cells to align and maintain cilia orientation in response to flow. May act by mediating a maturation step that stabilizes and aligns cilia orientation. Not required to respond to planar cell polarity (PCP) or flow-based orientation cues (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Note=Localizes to a polar structure adjacent to the basal body. {ECO:0000250}.
|
![Western Blot: CCDC176 Overexpression Lysate (Native) [NBP2-06248] - CCDC176 Overexpression Lysate (Native) Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for C14orf45.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10438_CCDC176-Overexpression-Lysate-(Native)-Western-Blot-NBP2-06248-img0002.jpg)