| Gene Symbol |
THNSL2
|
| Entrez Gene |
55258
|
| Alt Symbol |
SOFAT, THS2, TSH2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
threonine synthase-like 2 (S. cerevisiae)
|
| Other Description |
secreted osteoclastogenic factor of activated T cells|threonine synthase-like 2
|
| Swissprots |
D9ZZB8 B3KTB1 Q86YJ6 Q6PI27 B7WPF8 B5MDX8 Q6P2M7 Q9NV54
|
| Accessions |
AAX88906 EAW77072 EAW77073 EAW77074 Q86YJ6 AI313402 AK001778 BAA91904 AK092823 AK095303 BAG53023 AK289486 BAF82175 AK315831 BAF98722 AL832746 BC035315 AAH35315 BC047758 AAH47758 BC050699 BC064423 AAH64423 BI765911 DA044670 DA196694 DB024675 HM185274 ADL14696 XM_005264400 XP_005264457 XM_005264401 XP_005264458 XM_005264402 XP_005264459 XM_005264403 XP_005264460 XM_005264404 XP_005264461 XM_005264405 XP_005264462 XM_006712041 XP_006712104 XM_006712042 XP_006712105 XM_006712043 XP_006712106 XM_006712044 XP_006712107 XM_011532952 XP_011531254 XM_011532953 XP_011531255 XM_011532954 XP_011531256 XM_011532955 XP_011531257 NM_001244676 NP_001231605 NM_001244678 NP_001231607 NM_018271 NP_060741
|
| Function |
Isoform 1: Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates. Degrades O-phospho- threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Isoform SOFAT: Secreted. Note=Secreted by activated T-cells via a calcineurin-independent pathway.
|