Gene Symbol | THNSL2 |
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Entrez Gene | 55258 |
Alt Symbol | SOFAT, THS2, TSH2 |
Species | Human |
Gene Type | protein-coding |
Description | threonine synthase-like 2 (S. cerevisiae) |
Other Description | secreted osteoclastogenic factor of activated T cells|threonine synthase-like 2 |
Swissprots | D9ZZB8 B3KTB1 Q86YJ6 Q6PI27 B7WPF8 B5MDX8 Q6P2M7 Q9NV54 |
Accessions | AAX88906 EAW77072 EAW77073 EAW77074 Q86YJ6 AI313402 AK001778 BAA91904 AK092823 AK095303 BAG53023 AK289486 BAF82175 AK315831 BAF98722 AL832746 BC035315 AAH35315 BC047758 AAH47758 BC050699 BC064423 AAH64423 BI765911 DA044670 DA196694 DB024675 HM185274 ADL14696 XM_005264400 XP_005264457 XM_005264401 XP_005264458 XM_005264402 XP_005264459 XM_005264403 XP_005264460 XM_005264404 XP_005264461 XM_005264405 XP_005264462 XM_006712041 XP_006712104 XM_006712042 XP_006712105 XM_006712043 XP_006712106 XM_006712044 XP_006712107 XM_011532952 XP_011531254 XM_011532953 XP_011531255 XM_011532954 XP_011531256 XM_011532955 XP_011531257 NM_001244676 NP_001231605 NM_001244678 NP_001231607 NM_018271 NP_060741 |
Function | Isoform 1: Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates. Degrades O-phospho- threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate (By similarity). {ECO:0000250}. |
Subcellular Location | Isoform SOFAT: Secreted. Note=Secreted by activated T-cells via a calcineurin-independent pathway. |
THNSL2 CRISPR/Cas9 KO Plasmid (h) - sc-408906 from Santa Cruz Biotechnology
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THNSL2 HDR Plasmid (h) - sc-408906-HDR from Santa Cruz Biotechnology
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THNSL2 Double Nickase Plasmid (h) - sc-408906-NIC from Santa Cruz Biotechnology
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THNSL2 Double Nickase Plasmid (h2) - sc-408906-NIC-2 from Santa Cruz Biotechnology
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THNSL2 CRISPR Activation Plasmid (h) - sc-408906-ACT from Santa Cruz Biotechnology
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THNSL2 CRISPR Activation Plasmid (h2) - sc-408906-ACT-2 from Santa Cruz Biotechnology
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THNSL2 Lentiviral Activation Particles (h) - sc-408906-LAC from Santa Cruz Biotechnology
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THNSL2 Lentiviral Activation Particles (h2) - sc-408906-LAC-2 from Santa Cruz Biotechnology
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THNSL2 siRNA (h) - sc-94994 from Santa Cruz Biotechnology
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THNSL2 shRNA Plasmid (h) - sc-94994-SH from Santa Cruz Biotechnology
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THNSL2 shRNA (h) Lentiviral Particles - sc-94994-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU075531 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21313 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21313 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04272 from Sigma-Aldrich
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THNSL2 siRNA (Human) - CRJ0603 from Cohesion Biosciences
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THNSL2 - MBS8226666 from MyBioSource
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shRNA set against Human THNSL2 (NM_018271.4) - SHH426892 from Creative biogene
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Human THNSL2 siRNA - orb271104 from Biorbyt
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THNSL2 shRNA Plasmid (Human) - CHJ0603 from Cohesion Biosciences
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THNSL2 miRNA 3'UTR clone - MiUTR3H-11756 from Creative biogene
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