| Gene Symbol |
PRX
|
| Entrez Gene |
57716
|
| Alt Symbol |
CMT4F
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
periaxin
|
| Other Description |
-
|
| Swissprots |
Q9BXM0 Q9BXL9 Q9HCF2
|
| Accessions |
EAW56962 EAW56963 Q9BXM0 AB046840 BAB13446 AF321191 AAK19279 AF321192 AAK19280 BC067266 AAH67266 CD674402 XM_011527171 XP_011525473 NM_020956 NP_066007 NM_181882 NP_870998
|
| Function |
Seems to be required for maintenance of peripheral nerve myelin sheath. May have a role in axon-glial interactions, possibly by interacting with the cytoplasmic domains of integral membrane proteins such as myelin-associated glycoprotein in the periaxonal regions of the Schwann cell plasma membrane. May have a role in the early phases of myelin deposition.
|
| Subcellular Location |
Isoform 2: Cytoplasm {ECO:0000250}.
|
| Tissue Specificity |
Isoform 1 and isoform 2 are found in sciatic nerve and Schwann cells. {ECO:0000269|PubMed:11157804}.
|