Gene Symbol | PRX |
---|---|
Entrez Gene | 57716 |
Alt Symbol | CMT4F |
Species | Human |
Gene Type | protein-coding |
Description | periaxin |
Other Description | - |
Swissprots | Q9BXM0 Q9BXL9 Q9HCF2 |
Accessions | EAW56962 EAW56963 Q9BXM0 AB046840 BAB13446 AF321191 AAK19279 AF321192 AAK19280 BC067266 AAH67266 CD674402 XM_011527171 XP_011525473 NM_020956 NP_066007 NM_181882 NP_870998 |
Function | Seems to be required for maintenance of peripheral nerve myelin sheath. May have a role in axon-glial interactions, possibly by interacting with the cytoplasmic domains of integral membrane proteins such as myelin-associated glycoprotein in the periaxonal regions of the Schwann cell plasma membrane. May have a role in the early phases of myelin deposition. |
Subcellular Location | Isoform 2: Cytoplasm {ECO:0000250}. |
Tissue Specificity | Isoform 1 and isoform 2 are found in sciatic nerve and Schwann cells. {ECO:0000269|PubMed:11157804}. |
periaxin CRISPR/Cas9 KO Plasmid (h) - sc-404868 from Santa Cruz Biotechnology
|
||||||||
periaxin HDR Plasmid (h) - sc-404868-HDR from Santa Cruz Biotechnology
|
||||||||
periaxin Double Nickase Plasmid (h) - sc-404868-NIC from Santa Cruz Biotechnology
|
||||||||
periaxin Double Nickase Plasmid (h2) - sc-404868-NIC-2 from Santa Cruz Biotechnology
|
||||||||
periaxin CRISPR Activation Plasmid (h) - sc-404868-ACT from Santa Cruz Biotechnology
|
||||||||
periaxin CRISPR Activation Plasmid (h2) - sc-404868-ACT-2 from Santa Cruz Biotechnology
|
||||||||
periaxin Lentiviral Activation Particles (h) - sc-404868-LAC from Santa Cruz Biotechnology
|
||||||||
periaxin Lentiviral Activation Particles (h2) - sc-404868-LAC-2 from Santa Cruz Biotechnology
|
||||||||
periaxin siRNA (h) - sc-97670 from Santa Cruz Biotechnology
|
||||||||
periaxin shRNA Plasmid (h) - sc-97670-SH from Santa Cruz Biotechnology
|
||||||||
periaxin shRNA (h) Lentiviral Particles - sc-97670-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU061681 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN17558 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17558 from Sigma-Aldrich
|
||||||||
PRX siRNA (Human) - CRJ1656 from Cohesion Biosciences
|
||||||||
periaxin CRISPR/Cas9 KO Plasmid (h2) - sc-404868-KO-2 from Santa Cruz Biotechnology
|
||||||||
periaxin HDR Plasmid (h2) - sc-404868-HDR-2 from Santa Cruz Biotechnology
|
||||||||
shRNA set against Human PRX (NM_181882.2) - SHH384744 from Creative biogene
|
||||||||
shRNA set against Human PRX(NM_020956.2) - SHR145424 from Creative biogene
|
||||||||
shRNA set against Human PRX(NM_181882.2) - SHR145578 from Creative biogene
|
||||||||
Human PRX siRNA - orb272157 from Biorbyt
|
||||||||
PRX shRNA Plasmid (Human) - CHJ1656 from Cohesion Biosciences
|
||||||||
PRX miRNA 3'UTR clone - MiUTR1H-08346 from Creative biogene
|
||||||||
PRX miRNA 3'UTR clone - MiUTR1H-08347 from Creative biogene
|