ACTR3B

Gene Symbol ACTR3B
Entrez Gene 57180
Alt Symbol ARP11, ARP3BETA
Species Human
Gene Type protein-coding
Description ARP3 actin-related protein 3 homolog B (yeast)
Other Description ARP3-beta|actin-like protein 3B|actin-related protein 3-beta|actin-related protein 3B|actin-related protein ARP4|actin-related protein Arp11
Swissprots A8MTG1 Q96BT2 Q7Z526 Q9P1U1 B4DFW4
Accessions AAS07430 EAW80446 Q9P1U1 AA559050 AB209174 BAD92411 AF023453 AAC98904 AF086920 AAP97150 AK001198 BAG50867 AK294292 BAG57575 AK315534 BAG37914 AK316078 BAH14449 BC008682 AAH08682 BC015207 AAH15207 DB570472 DN601600 DQ894754 ABM85680 EU176295 ABW03746 XM_006716065 XP_006716128 XM_006716066 XP_006716129 XM_006716067 XP_006716130 XM_006716068 XP_006716131 XM_011516425 XP_011514727 XM_011516426 XP_011514728 XM_011516427 XP_011514729 XM_011516428 XP_011514730 XR_927492 NM_001040135 NP_001035225 NM_020445 NP_065178 NR_073000 NR_073001
Function Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors. {ECO:0000269|PubMed:14651955}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection {ECO:0000250}.
Tissue Specificity Detected in fetal brain. Detected throughout the adult brain, in neurons from gray matter, but not in white matter. Detected in liver, skeletal muscle and pancreas. Detected in lung adenocarcinoma cells with low metastatic potential, but not in lung adenocarcinoma cells with high metastatic potential. {ECO:0000269|PubMed:10806390, ECO:0000269|PubMed:11162478}.

Arp3β siRNA (h) - sc-105092 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Arp3β shRNA Plasmid (h) - sc-105092-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Arp3β shRNA (h) Lentiviral Particles - sc-105092-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU112861 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® esiRNA - EHU107531 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2788 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2788 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ACTR3B siRNA (Human) - CRJ1380 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ACTR3B - MBS8239232 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ACTR3B (NM_020445.5) - SHH231138 from Creative biogene

Category siRNA
Species Reactivities Human

ACTR3B shRNA Plasmid (Human) - CHJ1380 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ACTR3B miRNA 3'UTR clone - MiUTR3H-16947 from Creative biogene

Species Reactivities Human

ACTR3B miRNA 3'UTR clone - MiUTR3H-16948 from Creative biogene

Species Reactivities Human
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