PARP10

Gene Symbol PARP10
Entrez Gene 84875
Alt Symbol ARTD10
Species Human
Gene Type protein-coding
Description poly (ADP-ribose) polymerase family, member 10
Other Description ADP-ribosyltransferase diphtheria toxin-like 10|PARP-10|poly [ADP-ribose] polymerase 10
Swissprots Q53GL7 Q96CH7 Q96K72 Q8WV05 Q8N2I0
Accessions EAW82169 Q53GL7 AI470346 AK027370 BAB55067 AK075250 BAC11498 AK124017 AK128537 BAG54691 AK129821 AK222914 BAD96634 AK303317 BAG64386 AK308657 AK309251 BC014229 AAH14229 BC019030 AAH19030 BC020378 BC030549 BC035485 BC132961 AAI32962 BC136542 AAI36543 BC144235 DA124793 XM_005251081 XP_005251138 XM_011517336 XP_011515638 XR_928358 NM_032789 NP_116178
Function May play a role in cell proliferation. May be required for the maintenance of cell cycle progression. {ECO:0000269|PubMed:15674325, ECO:0000269|PubMed:16455663}.
Subcellular Location Nucleus, nucleolus {ECO:0000269|PubMed:15674325}. Cytoplasm {ECO:0000269|PubMed:15674325}. Note=Shuttles between the nuclear and cytoplasmic compartment. A subpopulation concentrates in the nucleolus during late G1/S phase.
Tissue Specificity Highly expressed in spleen and thymus. Intermediate levels in liver, kidney, pancreas, prostate, testis, ovary, intestine, and leukocytes. Low expression in heart, brain, placenta, lung, skeletal muscle, and colon. {ECO:0000269|PubMed:15674325}.

Human PARP10 ORF clone (NM_032789.3) - CDCL146019 from Creative biogene

Species Human
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