Gene Symbol | PARP10 |
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Entrez Gene | 84875 |
Alt Symbol | ARTD10 |
Species | Human |
Gene Type | protein-coding |
Description | poly (ADP-ribose) polymerase family, member 10 |
Other Description | ADP-ribosyltransferase diphtheria toxin-like 10|PARP-10|poly [ADP-ribose] polymerase 10 |
Swissprots | Q53GL7 Q96CH7 Q96K72 Q8WV05 Q8N2I0 |
Accessions | EAW82169 Q53GL7 AI470346 AK027370 BAB55067 AK075250 BAC11498 AK124017 AK128537 BAG54691 AK129821 AK222914 BAD96634 AK303317 BAG64386 AK308657 AK309251 BC014229 AAH14229 BC019030 AAH19030 BC020378 BC030549 BC035485 BC132961 AAI32962 BC136542 AAI36543 BC144235 DA124793 XM_005251081 XP_005251138 XM_011517336 XP_011515638 XR_928358 NM_032789 NP_116178 |
Function | May play a role in cell proliferation. May be required for the maintenance of cell cycle progression. {ECO:0000269|PubMed:15674325, ECO:0000269|PubMed:16455663}. |
Subcellular Location | Nucleus, nucleolus {ECO:0000269|PubMed:15674325}. Cytoplasm {ECO:0000269|PubMed:15674325}. Note=Shuttles between the nuclear and cytoplasmic compartment. A subpopulation concentrates in the nucleolus during late G1/S phase. |
Tissue Specificity | Highly expressed in spleen and thymus. Intermediate levels in liver, kidney, pancreas, prostate, testis, ovary, intestine, and leukocytes. Low expression in heart, brain, placenta, lung, skeletal muscle, and colon. {ECO:0000269|PubMed:15674325}. |
PARP-10 CRISPR/Cas9 KO Plasmid (h) - sc-406703 from Santa Cruz Biotechnology
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PARP-10 HDR Plasmid (h) - sc-406703-HDR from Santa Cruz Biotechnology
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PARP-10 Double Nickase Plasmid (h) - sc-406703-NIC from Santa Cruz Biotechnology
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PARP-10 Double Nickase Plasmid (h2) - sc-406703-NIC-2 from Santa Cruz Biotechnology
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PARP-10 CRISPR Activation Plasmid (h) - sc-406703-ACT from Santa Cruz Biotechnology
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PARP-10 CRISPR Activation Plasmid (h2) - sc-406703-ACT-2 from Santa Cruz Biotechnology
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PARP-10 Lentiviral Activation Particles (h) - sc-406703-LAC from Santa Cruz Biotechnology
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PARP-10 Lentiviral Activation Particles (h2) - sc-406703-LAC-2 from Santa Cruz Biotechnology
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PARP-10 siRNA (h) - sc-63306 from Santa Cruz Biotechnology
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PARP-10 shRNA Plasmid (h) - sc-63306-SH from Santa Cruz Biotechnology
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PARP-10 shRNA (h) Lentiviral Particles - sc-63306-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU124201 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16342 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16342 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01828 from Sigma-Aldrich
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PARP10 siRNA (Human) - CRJ3658 from Cohesion Biosciences
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shRNA set against Human PARP10 (NM_032789.3) - SHH370824 from Creative biogene
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Human PARP10 siRNA - orb274159 from Biorbyt
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PARP10 shRNA Plasmid (Human) - CHJ3658 from Cohesion Biosciences
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PARP10 miRNA 3'UTR clone - MiUTR1H-07518 from Creative biogene
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