| Gene Symbol |
SPINK13
|
| Entrez Gene |
153218
|
| Alt Symbol |
HBVDNAPTP1, HESPINTOR, LiESP6, SPINK5L3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
serine peptidase inhibitor, Kazal type 13 (putative)
|
| Other Description |
Hepatitis B Virus (HBV) DNA polymerase transactivated protein 1|hepatitis B virus DNA polymerase transactivated human serine protease inhibitor|hepatitis B virus DNA polymerase transactivated serine protease inhibitor|serine protease inhibitor Kazal-type 13|serine protease inhibitor Kazal-type 5-like 3
|
| Swissprots |
Q1W4C9 A1A4Y2
|
| Accessions |
EAW61812 Q1W4C9 AK001520 BC128163 AAI28164 BC128164 AAI28165 DQ438947 ABD96086 EF108324 ABO28598 EF426754 ABR09863 NM_001040129 NP_001035218
|
| Function |
May be a serine protease inhibitor (By similarity). Essential for sperm maturation and fertility. Inhibits sperm acrosome reaction, protecting sperm from premature reaction (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Secreted {ECO:0000250}. Note=Secreted into the lumen of the initial segment of the epididymis and binds to sperm. In the initial segment of epididymis, localizes on the dorsal surface of the acrosomal region of sperm, gradually becomes more restricted to the acrosomal region in spermatozoa during epididymal transit (By similarity). {ECO:0000250}.
|
![Western Blot: SPINK13 Overexpression Lysate (Adult Normal) [NBP2-08502] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SPINK13.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5799_SPINK13%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-08502-img0001.jpg)