Gene Symbol | SPINK13 |
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Entrez Gene | 153218 |
Alt Symbol | HBVDNAPTP1, HESPINTOR, LiESP6, SPINK5L3 |
Species | Human |
Gene Type | protein-coding |
Description | serine peptidase inhibitor, Kazal type 13 (putative) |
Other Description | Hepatitis B Virus (HBV) DNA polymerase transactivated protein 1|hepatitis B virus DNA polymerase transactivated human serine protease inhibitor|hepatitis B virus DNA polymerase transactivated serine protease inhibitor|serine protease inhibitor Kazal-type 13|serine protease inhibitor Kazal-type 5-like 3 |
Swissprots | Q1W4C9 A1A4Y2 |
Accessions | EAW61812 Q1W4C9 AK001520 BC128163 AAI28164 BC128164 AAI28165 DQ438947 ABD96086 EF108324 ABO28598 EF426754 ABR09863 NM_001040129 NP_001035218 |
Function | May be a serine protease inhibitor (By similarity). Essential for sperm maturation and fertility. Inhibits sperm acrosome reaction, protecting sperm from premature reaction (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted {ECO:0000250}. Note=Secreted into the lumen of the initial segment of the epididymis and binds to sperm. In the initial segment of epididymis, localizes on the dorsal surface of the acrosomal region of sperm, gradually becomes more restricted to the acrosomal region in spermatozoa during epididymal transit (By similarity). {ECO:0000250}. |
SPINK5L3 CRISPR/Cas9 KO Plasmid (h) - sc-414729 from Santa Cruz Biotechnology
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SPINK5L3 HDR Plasmid (h) - sc-414729-HDR from Santa Cruz Biotechnology
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SPINK5L3 Double Nickase Plasmid (h) - sc-414729-NIC from Santa Cruz Biotechnology
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SPINK5L3 Double Nickase Plasmid (h2) - sc-414729-NIC-2 from Santa Cruz Biotechnology
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SPINK5L3 CRISPR Activation Plasmid (h) - sc-414729-ACT from Santa Cruz Biotechnology
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SPINK5L3 CRISPR Activation Plasmid (h2) - sc-414729-ACT-2 from Santa Cruz Biotechnology
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SPINK5L3 Lentiviral Activation Particles (h) - sc-414729-LAC from Santa Cruz Biotechnology
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SPINK5L3 Lentiviral Activation Particles (h2) - sc-414729-LAC-2 from Santa Cruz Biotechnology
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SPINK5L3 siRNA (h) - sc-92047 from Santa Cruz Biotechnology
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SPINK5L3 shRNA Plasmid (h) - sc-92047-SH from Santa Cruz Biotechnology
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SPINK5L3 shRNA (h) Lentiviral Particles - sc-92047-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN20479 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20479 from Sigma-Aldrich
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SPINK13 siRNA (Human) - CRJ5760 from Cohesion Biosciences
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SPINK13 - MBS8236629 from MyBioSource
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shRNA set against Human SPINK13 (NM_001040129.2) - SHH416748 from Creative biogene
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shRNA set against Human SPINK5L3(NM_001040129.2) - SHL029116 from Creative biogene
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Human SPINK13 siRNA - orb276261 from Biorbyt
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SPINK13 shRNA Plasmid (Human) - CHJ5760 from Cohesion Biosciences
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SPINK13 miRNA 3'UTR clone - MiUTR1H-09846 from Creative biogene
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