CYP3A43
| Gene Symbol | CYP3A43 |
|---|---|
| Entrez Gene | 64816 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | cytochrome P450, family 3, subfamily A, polypeptide 43 |
| Other Description | cytochrome P450 3A43|cytochrome P450, subfamily IIIA, polypeptide 43 |
| Swissprots | Q9HB57 Q75MK3 Q9HB55 Q75MK2 Q495Y1 Q9HB53 Q9HB52 Q9HB54 |
| Accessions | AAG32291 AAS07394 AAS07395 EAW76630 EAW76631 EAW76632 EAW76633 EAW76634 Q9HB55 AA417369 AF280108 AAG33009 AF280109 AAG33010 AF280110 AAG33011 AF280111 AAG33012 AF280112 AAG33013 AF280113 AAG33014 AF319634 AAK00325 AF337813 AAK38841 AY390423 AAQ92351 AY390424 AAQ92352 AY390425 AAQ92353 AY390426 AAQ92354 BC100981 AAI00982 BC100982 AAI00983 XM_011516493 XP_011514795 XM_011516494 XP_011514796 NM_001278921 NP_001265850 NM_022820 NP_073731 NM_057095 NP_476436 NM_057096 NP_476437 NR_103868 NR_103869 |
| Function | Exhibits low testosterone 6-beta-hydroxylase activity. |
| Subcellular Location | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. |
| Tissue Specificity | Highest expression level in prostate. Also expressed in liver, kidney, pancreas, fetal liver and fetal skeletal muscle. {ECO:0000269|PubMed:11160876, ECO:0000269|PubMed:11243885}. |
| Top Pathways | Chemical carcinogenesis |
CYP3A43 CRISPR/Cas9 KO Plasmid (h) - sc-407003 from Santa Cruz Biotechnology
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CYP3A43 HDR Plasmid (h) - sc-407003-HDR from Santa Cruz Biotechnology
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CYP3A43 Double Nickase Plasmid (h) - sc-407003-NIC from Santa Cruz Biotechnology
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CYP3A43 Double Nickase Plasmid (h2) - sc-407003-NIC-2 from Santa Cruz Biotechnology
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CYP3A43 CRISPR Activation Plasmid (h) - sc-407003-ACT from Santa Cruz Biotechnology
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CYP3A43 CRISPR Activation Plasmid (h2) - sc-407003-ACT-2 from Santa Cruz Biotechnology
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CYP3A43 Lentiviral Activation Particles (h) - sc-407003-LAC from Santa Cruz Biotechnology
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CYP3A43 Lentiviral Activation Particles (h2) - sc-407003-LAC-2 from Santa Cruz Biotechnology
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CYP3A43 siRNA (h) - sc-105258 from Santa Cruz Biotechnology
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CYP3A43 shRNA Plasmid (h) - sc-105258-SH from Santa Cruz Biotechnology
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CYP3A43 shRNA (h) Lentiviral Particles - sc-105258-V from Santa Cruz Biotechnology
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CYP3A43 RNAi - H00064816-R01 from Novus Biologicals
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CYP3A43 RNAi - H00064816-R03 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN2524 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2524 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05110 from Sigma-Aldrich
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CYP3A43 siRNA (Human) - CRJ2106 from Cohesion Biosciences
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CYP3A43 RNAi - H00064816-R02 from Novus Biologicals
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CYP3A43 - MBS8202424 from MyBioSource
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shRNA set against Human CYP3A43 (NM_022820.3) - SHH273497 from Creative biogene
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shRNA set against Human CYP3A43(NM_057096.2) - SHG217627 from Creative biogene
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shRNA set against Human CYP3A43(NM_057095.1) - SHG217645 from Creative biogene
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Human CYP3A43 siRNA - orb272607 from Biorbyt
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CYP3A43 shRNA Plasmid (Human) - CHJ2106 from Cohesion Biosciences
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CYP3A43 miRNA 3'UTR clone - MiUTR1H-02631 from Creative biogene
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