Gene Symbol | CYP3A43 |
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Entrez Gene | 64816 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | cytochrome P450, family 3, subfamily A, polypeptide 43 |
Other Description | cytochrome P450 3A43|cytochrome P450, subfamily IIIA, polypeptide 43 |
Swissprots | Q9HB57 Q75MK3 Q9HB55 Q75MK2 Q495Y1 Q9HB53 Q9HB52 Q9HB54 |
Accessions | AAG32291 AAS07394 AAS07395 EAW76630 EAW76631 EAW76632 EAW76633 EAW76634 Q9HB55 AA417369 AF280108 AAG33009 AF280109 AAG33010 AF280110 AAG33011 AF280111 AAG33012 AF280112 AAG33013 AF280113 AAG33014 AF319634 AAK00325 AF337813 AAK38841 AY390423 AAQ92351 AY390424 AAQ92352 AY390425 AAQ92353 AY390426 AAQ92354 BC100981 AAI00982 BC100982 AAI00983 XM_011516493 XP_011514795 XM_011516494 XP_011514796 NM_001278921 NP_001265850 NM_022820 NP_073731 NM_057095 NP_476436 NM_057096 NP_476437 NR_103868 NR_103869 |
Function | Exhibits low testosterone 6-beta-hydroxylase activity. |
Subcellular Location | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. |
Tissue Specificity | Highest expression level in prostate. Also expressed in liver, kidney, pancreas, fetal liver and fetal skeletal muscle. {ECO:0000269|PubMed:11160876, ECO:0000269|PubMed:11243885}. |
Top Pathways | Chemical carcinogenesis |
CYP3A (I-16) - sc-30617 from Santa Cruz Biotechnology
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CYP3A43 (E-9) - sc-393860 from Santa Cruz Biotechnology
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CYP3A43 (H-41) - sc-368034 from Santa Cruz Biotechnology
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Anti-CYP3A43 antibody - ab155029 from Abcam
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Anti-CYP3A43 antibody - ab89252 from Abcam
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Anti-CYP3A43 antibody - ab94940 from Abcam
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Anti-CYP3A43 antibody - ab69649 from Abcam
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Anti-CYP3A43 antibody - ab68754 from Abcam
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Anti-CYP3A43 antibody - N-terminal - ab82849 from Abcam
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Anti-CYP3A43 Antibody (aa231-280) - LS-C119505 from LifeSpan Bioscience
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Anti-CYP3A43 Antibody (aa249-278) - LS-C167231 from LifeSpan Bioscience
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Anti-CYP3A43 Antibody (aa398-447) IHC-plus™ - LS-B10884 from LifeSpan Bioscience
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Anti-CYP3A43 Antibody (aa254-303) IHC-plus™ - LS-B10883 from LifeSpan Bioscience
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CYP3A43 Antibody - NBP2-16064 from Novus Biologicals
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CYP3A43 Antibody - H00064816-B01 from Novus Biologicals
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CYP3A43 Antibody - NBP1-69370 from Novus Biologicals
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CYP3A43 Antibody - NBP1-69413 from Novus Biologicals
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CYP3A43 Antibody - H00064816-D01 from Novus Biologicals
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Anti-CYP3A43 (ab2) antibody produced in rabbit - SAB2100522 from Sigma-Aldrich
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Anti-CYP3A43 (ab1) antibody produced in rabbit - SAB2100521 from Sigma-Aldrich
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Anti-CYP3A43 antibody produced in mouse - SAB1400680 from Sigma-Aldrich
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Anti-Cytochrome P450 3A43 antibody produced in rabbit - SAB4502781 from Sigma-Aldrich
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CYP3A43 antibody - middle region (ARP49757_P050) - ARP49757_P050 from Aviva Systems Biology
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CYP3A43 antibody - C-terminal region (ARP49758_P050) - ARP49758_P050 from Aviva Systems Biology
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CYP3A43-Antibody-Center - AP7999c from Abgent, a WuXi AppTec company
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